Complex 8h0s
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.90 |
| System mass | 101.37 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bacillus |
| RCSB PDB Entry | 8h0s |
| Reference | Cho Gyuhyeok, Lee Jangmin, Kim Jungwook. 2023. Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification Nucleic Acids Research |
| Equivalence Class |
NR_all_76339.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAM |
| Residue | . / 301 |
| Chain | G / A |
| Non-redundant | True |
| Interacting RNA chains | E/X |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | E/X: unknown |
| RNA family global | unknown |
| Volume | 191.39 Å3 |
| Hydrophobicity | 1.113 |
| Hydrophilicity | 1.308 |
| Buriedness | 0.868 |
| Don/acc character | 0.500 |
| SiteScore | 1.114 |
| D Score | 1.035 |
| Kd | — |
| Compound | SAM |
| Residue | . / 301 |
| Chain | I / C |
| Non-redundant | True |
| Interacting RNA chains | F/Y |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | F/Y: unknown |
| RNA family global | unknown |
| Volume | 191.74 Å3 |
| Hydrophobicity | 1.018 |
| Hydrophilicity | 1.142 |
| Buriedness | 0.816 |
| Don/acc character | 0.702 |
| SiteScore | 1.079 |
| D Score | 1.057 |
| Kd | — |