Complex 8eyu
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.95 |
| System mass | 32.89 kDa |
| Deposition year | 2022 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 8eyu |
| Reference | Passalacqua Luiz F. M., Starich Mary R., Link Katie A., Wu Jiahui, Knutson Jay R., Tjandra Nico, Jaffrey Samie R., Ferré-D’Amaré Adrian R.. 2023. Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture Nature Communications |
| Equivalence Class |
NR_all_98067.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | X5R |
| Residue | . / 103 |
| Chain | E / B |
| Non-redundant | True |
| Interacting RNA chains | A/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 231.53 Å3 |
| Hydrophobicity | 1.161 |
| Hydrophilicity | 0.564 |
| Buriedness | 0.591 |
| Don/acc character | 3.203 |
| SiteScore | 1.170 |
| D Score | 1.111 |
| Kd | — |
| Compound | X5R |
| Residue | . / 104 |
| Chain | I / A |
| Non-redundant | True |
| Interacting RNA chains | B/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/A: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 196.88 Å3 |
| Hydrophobicity | 1.203 |
| Hydrophilicity | 0.621 |
| Buriedness | 0.629 |
| Don/acc character | 4.636 |
| SiteScore | 1.163 |
| D Score | 1.087 |
| Kd | — |