Complex 8g7r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.80 |
| System mass | 2239.91 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 8g7r |
| Reference | Rybak Mariia Yu., Gagnon Matthieu G.. 2024. Structures of the ribosome bound to EF-Tu–isoleucine tRNA elucidate the mechanism of AUG avoidance Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_83717.187,
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PAR |
| Residue | . / 1601 |
| Chain | EB / a |
| Non-redundant | True |
| Interacting RNA chains | A/a |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/a: rRNA |
| RNA family global | rRNA |
| Volume | 260.34 Å3 |
| Hydrophobicity | 0.202 |
| Hydrophilicity | 1.103 |
| Buriedness | 0.692 |
| Don/acc character | 1.223 |
| SiteScore | 0.894 |
| D Score | 0.864 |
| Kd | — |