Complex 8gh6
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.08 |
| System mass | 255.81 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | Bombyx |
| RCSB PDB Entry | 8gh6 |
| Reference | Wilkinson Max E., Frangieh Chris J., Macrae Rhiannon K., Zhang Feng. 2023. Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription Science |
| Equivalence Class |
NR_all_32978.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | TTP |
| Residue | . / 1204 |
| Chain | I / A |
| Non-redundant | True |
| Interacting RNA chains | D/R |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | D/R: unknown |
| RNA family global | unknown |
| Volume | 488.78 Å3 |
| Hydrophobicity | 0.570 |
| Hydrophilicity | 1.355 |
| Buriedness | 0.814 |
| Don/acc character | 0.454 |
| SiteScore | 1.078 |
| D Score | 0.987 |
| Kd | — |