Harnessing RIBOnucleic acid - Small molecules Structures
E. coli 70S ribosome complex (N1-methylated 16S A1408 + arbekacin)
SM: 84G
E. coli 70S ribosome complex (unmethylated 16S A1408 + arbekacin)
E. coli 70S ribosome complex (N1-methylated 16S A1408 + G418)
SM: GET
RhoBAST aptamer RNA in complex with 5(6)-carboxytetramethylrhodamine
SM: FH8
Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs
SM: AMZ
Cutibacterium acnes 50S ribosomal subunit with Clindamycin bound
SM: CLY
Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate
SM: TPP
Human 39S mitoribosome in complex with antibiotic Linezolid
SM: ZLD
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
SM: MQC
SM: A1AZM
SM: A1AZL
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin and protein Y at 2.60A resolution
SM: ARG
Rous sarcoma virus frameshifting pseudoknot RNA
SM: TAM
NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.
NMR structures of small molecules bound to a model of an RNA CAG repeat expansion
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B
SM: HYG
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B, Class II
RhoBAST RNA aptamer in complex with the SpyRho555 analogue, MaP555
SM: A1BC9
Cryo-EM structure of the Pyrobaculum calidifontis 50S ribosomal subunit in complex with Dri
SM: SPM
Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome
Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome in complex with Dri
Structure of the Bacillus subtilis yjdF riboswitch complexed with lumichrome in the presence of iridium hexammine
SM: LUM
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with lumichrome
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with chelerythrine
SM: CTI
Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK
Structure of E. coli 30S-IF1-IF3-mRNA-Kasugamycin complex
SM: KSG
Structure of E. coli 30S-IF1-IF3-mRNA-Edeine complex
SM: EDE
High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA
Crystal structure of the alkyltransferase ribozyme SAMURI co-crystallized with SAM
SM: SAH
Crystal structure of the alkyltransferase ribozyme SAMURI co-crystalized with ProSeDMA
SM: A1IY6
CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1
SM: 3HE ANM GDP HYG
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA with h44 in up position
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aEF1A-like mRNA
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA with h44 in up position
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA : LM32CS1C1 M2 OE MUTANT
SM: PAR
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA
Structure of Candida albicans 80S ribosome in complex with mefloquine (non-rotated state)
SM: SPK YMZ
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA
SM: GET SPK
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA
SM: GET SPK YMZ
E. coli 70S-TEC complex in delivery state
SM: PHE
70S ribosome with doublet-decoding tRNASer3 bound to A-site GCA codon
70S ribosome with cognate tRNASer3 bound to A-site AGC codon
Assembly intermediate of human mitochondrial ribosome small subunit in complex with PUS1, METTL15 and RBFA(IN conformation) (state M1)
SM: NAD SPM
Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine
SM: EPE TER
Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH P/E-site tRNA AND mRNA : LM14Cs1H3 sKO STRAIN
SM: A1IWA
Crystal structure of the Class V GTP aptamer in complex with GTP
SM: GTP
Crystal structure of the Class V (UU) GTP aptamer variant in complex with GTP
Crystal structure of the Class V (G61A) GTP aptamer variant in complex with GTP
Solution NMR structure of the synthetic tobramycin riboswitch in complex with tobramycin
SM: TOY
CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATE
50S subunit of P. gingivalis ribosome with Lefamulin
SM: 62B
Structure of the wild-type Staphylococcus aureus 70S ribosome complexed with clincelin
SM: A1I09
Structure of the A2058-dimethylated Staphylococcus aureus 70S ribosome complexed with clincelin
Current selection range: to