Harnessing RIBOnucleic acid - Small molecules Structures
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Crystal structure of folE riboswitch with 8-N Guanine
SM: SPM
Crystal structure of folE riboswitch with 8-NH2 Guanine
SM: ANG SPM
Crystal structure of THF-II riboswitch with THF and soaked with Ir
SM: SPM THG
Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound
SM: A1LYK
SM: A1LYL
RNA duplex containing Formamide
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
SM: T1C T1C T1C T1C T1C T1C
Solution structure of the complex of naphthyridine-azaquinolone and an RNA with ACG/AUA motif
SM: NAZ
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with berberine analog of chloramphenicol CAM-BER, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.80A resolution
SM: A1AIX A1AIX
E. coli 70S ribosome complex (N1-methylated 16S A1408 + arbekacin)
SM: 84G 84G
E. coli 70S ribosome complex (unmethylated 16S A1408 + arbekacin)
E. coli 70S ribosome complex (N1-methylated 16S A1408 + G418)
SM: GET GET
RhoBAST aptamer RNA in complex with 5(6)-carboxytetramethylrhodamine
SM: FH8 FH8 FH8 FH8
Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs
SM: AMZ
Cutibacterium acnes 50S ribosomal subunit with Clindamycin bound
SM: CLY
Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate
SM: TPP
Human 39S mitoribosome in complex with antibiotic Linezolid
SM: ZLD
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
SM: MQC
SM: A1AZM
SM: A1AZL
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin and protein Y at 2.60A resolution
SM: ARG
Rous sarcoma virus frameshifting pseudoknot RNA
SM: TAM
NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.
NMR structures of small molecules bound to a model of an RNA CAG repeat expansion
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B
SM: HYG
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B, Class II
RhoBAST RNA aptamer in complex with the SpyRho555 analogue, MaP555
SM: A1BC9
Cryo-EM structure of the Pyrobaculum calidifontis 50S ribosomal subunit in complex with Dri
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome in complex with Dri
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Structure of the Bacillus subtilis yjdF riboswitch complexed with lumichrome in the presence of iridium hexammine
SM: LUM LUM
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with lumichrome
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with chelerythrine
SM: CTI CTI
Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E
SM: SPM SPM SPM
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK
Structure of E. coli 30S-IF1-IF3-mRNA-Kasugamycin complex
SM: KSG
Structure of E. coli 30S-IF1-IF3-mRNA-Edeine complex
SM: EDE
High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Crystal structure of the alkyltransferase ribozyme SAMURI co-crystallized with SAM
SM: SAH SAH
Crystal structure of the alkyltransferase ribozyme SAMURI co-crystalized with ProSeDMA
SM: A1IY6 A1IY6
CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1
SM: 3HE ANM GDP HYG
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA with h44 in up position
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aEF1A-like mRNA
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA with h44 in up position
SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA : LM32CS1C1 M2 OE MUTANT
SM: PAR PAR PAR PAR PAR PAR
Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA
Structure of Candida albicans 80S ribosome in complex with mefloquine (non-rotated state)
SM: SPK YMZ YMZ
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA
SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK
The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA
SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK YMZ
E. coli 70S-TEC complex in delivery state
SM: PHE
70S ribosome with doublet-decoding tRNASer3 bound to A-site GCA codon
70S ribosome with cognate tRNASer3 bound to A-site AGC codon
Assembly intermediate of human mitochondrial ribosome small subunit in complex with PUS1, METTL15 and RBFA(IN conformation) (state M1)
SM: NAD SPM
Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine
SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER
Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8