Complex 9b50
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.70 |
| System mass | 2147.43 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 9b50 |
| Reference | Dey Debayan, Mattingly Jacob M., Zelinskaya Natalia, Dunham Christine M., Conn Graeme L.. 2025. Basis for selective drug evasion of an aminoglycoside-resistance ribosomal RNA modification Nature Communications |
| Equivalence Class |
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 84G |
| Residue | . / 1694 |
| Chain | PE / AA |
| Non-redundant | False |
| Interacting RNA chains | A/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 100.16 Å3 |
| Hydrophobicity | 0.091 |
| Hydrophilicity | 0.882 |
| Buriedness | 0.569 |
| Don/acc character | 3.695 |
| SiteScore | 0.842 |
| D Score | 0.671 |
| Kd | — |
| Compound | 84G |
| Residue | . / 1695 |
| Chain | QE / AA |
| Non-redundant | False |
| Interacting RNA chains | A/AA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 237.70 Å3 |
| Hydrophobicity | 0.018 |
| Hydrophilicity | 1.113 |
| Buriedness | 0.658 |
| Don/acc character | 2.158 |
| SiteScore | 0.943 |
| D Score | 0.741 |
| Kd | — |