HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9fn3

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.90
System mass 38.68 kDa
Deposition year 2024
Molecule type RNA
# RNA entities 1
Organism N/A
RCSB PDB Entry 9fn3
Reference Chen Hsuan-Ai, Okuda Takumi, Lenz Ann-Kathrin, Scheitl Carolin P. M., Schindelin Hermann, Höbartner Claudia. 2026. Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI Nature Chemical Biology
Equivalence Class NR_all_22241.3, NR_all_72735.3
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound A1IY6
Residue . / 101
Chain C / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled ion
RNA environment global RNA
RNA family chains A/A: ribozyme
RNA family global ribozyme
Volume 585.50 Å3
Hydrophobicity 0.572
Hydrophilicity 0.943
Buriedness 0.681
Don/acc character 1.824
SiteScore 1.158
D Score 1.041
Kd

Compound A1IY6
Residue . / 101
Chain G / B
Non-redundant False
Interacting RNA chains B/B
RNA environment detailled ion
RNA environment global RNA
RNA family chains B/B: ribozyme
RNA family global ribozyme
Volume 533.37 Å3
Hydrophobicity 0.675
Hydrophilicity 0.925
Buriedness 0.676
Don/acc character 1.589
SiteScore 1.157
D Score 1.044
Kd