HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Compound A1BC9

Identifiers

  • Canonical SMILES:
    CN(C)c1ccc2c(OC3=CC(C=CC3=C2c4cc(ccc4C(=O)N[S](=O)(=O)N(C)C)C(O)=O)=[N](C)C)c1
  • InChi:
    InChI=1S/C27H29N4O6S/c1-29(2)17-8-11-20-23(14-17)37-24-15-18(30(3)4)9-12-21(24)25(20)22-13-16(27(33)34)7-10-19(22)26(32)28-38(35,36)31(5)6/h7-15H,1-6H3,(H,28,32)(H,33,34)
  • InChiKey:
    WYGUIDZIZZOQBY-UHFFFAOYSA-N

Chemistry rules

Lipinski's RO5 Veber Pfizer's 3/75

RNA-SM complexes

PDB code Deposition date Reference publication
9dxl Oct. 11, 2024 Siwik Shea H, Wierzba Aleksandra J, Lennon Shelby R, Olenginski Lukasz T, Palmer Amy E, Batey Robert T. . Structural basis for ring-opening fluorescence by the RhoBAST RNA aptamer Nucleic Acids Research

Physicochemical filters

Descriptor Lipinski's RO5 Veber Pfizer's 3/75
Compliance
MW 537.61 g/mol
HBA not available
HBD not available
HBA + HBD
AlogP not available
TPSA not available
RB not available

Radar chart