HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 8znq

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Solution NMR
Experimental resolution N/A
System mass 10.07 kDa
Deposition year 2024
Molecule type RNA
# RNA entities 1
Organism Homo
RCSB PDB Entry 8znq
Reference Chen Qingwen, Fujiwara Aina, Nakatani Kazuhiko, Kawai Gota, Murata Asako. 2025. Identification and structural insights into RNA motifs targeted by a CAG repeat DNA-binding small molecule Chemical Science
Equivalence Class NR_all_72265.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound NAZ
Residue . / 101
Chain B / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains A/A: unknown
RNA family global unknown
Volume 109.07 Å3
Hydrophobicity 0.288
Hydrophilicity 1.019
Buriedness 0.623
Don/acc character 1.411
SiteScore 0.453
D Score 0.582
Kd