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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 7azy

7azy

Context-specific inhibition of eukaryotic translation by macrolide antibiotics

SM: TEL

Structure of complex 7b5k

7b5k

E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain.

SM: ERY SY5 SY5

Structure of complex 7bt6

7bt6

Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)

SM: GTP

Structure of complex 7btb

7btb

Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)

SM: GTP

Structure of complex 7ctt

7ctt

Cryo-EM structure of Favipiravir bound to replicating polymerase complex of SARS-CoV-2 in the pre-catalytic state.

SM: GE6

Structure of complex 7d7v

7d7v

Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein

SM: GTP NAD

Structure of complex 7d8c

7d8c

Crystal structure of the Cas12i1-crRNA binary complex

SM: CIT

Structure of complex 7dug

7dug

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1''TFMS bound

SM: HJR

Structure of complex 7duh

7duh

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1''AC bound

SM: HJO

Structure of complex 7dui

7dui

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1''PyrS bound

SM: HKO

Structure of complex 7duj

7duj

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1,3''Bz bound

SM: SIS

Structure of complex 7duk

7duk

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1,3''MS bound

SM: SIS

Structure of complex 7dul

7dul

Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N3''MS bound

SM: SIS

Structure of complex 7dwh

7dwh

Complex structure of SAM-dependent methyltransferase ribozyme

SM: SAM SAM

Structure of complex 7ed5

7ed5

A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

SM: AT9

Structure of complex 7f0d

7f0d

Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin

SM: CTY

Structure of complex 7jyy

7jyy

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).

SM: SAM SAM

Structure of complex 7jz0

7jz0

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

SM: SAH SAH

Structure of complex 7k00

7k00

Structure of the Bacterial Ribosome at 2 Angstrom Resolution

SM: PAR SPM

Structure of complex 7k51

7k51

Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II)

SM: GCP

Structure of complex 7k55

7k55

Near post-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure III-FS)

SM: GCP

Structure of complex 7k98

7k98

Preaminoacylation complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine (F-AMS)

SM: W5Y W5Y

Structure of complex 7k9d

7k9d

Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (crystal form I)

SM: EPE

Structure of complex 7kkv

7kkv

Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (native, crystal form I)

SM: EPE

Structure of complex 7l6r

7l6r

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn).

SM: SAH

Structure of complex 7l6t

7l6t

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions.

SM: SAH

Structure of complex 7lh5

7lh5

Crystal structure of the Thermus thermophilus 70S ribosome in complex with plazomicin, mRNA and tRNAs

SM: EDS EDS

Structure of complex 7m4u

7m4u

A. baumannii Ribosome-Eravacycline complex: 30S

SM: YQM

Structure of complex 7m4v

7m4v

A. baumannii Ribosome-Eravacycline complex: 50S

SM: YQM YQM

Structure of complex 7m4w

7m4w

A. baumannii Ribosome-Eravacycline complex: Empty 70S

SM: YQM YQM YQM

Structure of complex 7m4x

7m4x

A. baumannii Ribosome-Eravacycline complex: P-site tRNA 70S

SM: YQM YQM YQM

Structure of complex 7m4y

7m4y

A. baumannii Ribosome-Eravacycline complex: E-site tRNA 70S

SM: YQM YQM YQM

Structure of complex 7m4z

7m4z

A. baumannii Ribosome-Eravacycline complex: hpf-bound 70S

SM: YQM YQM

Structure of complex 7md7

7md7

Crystal structure of the Thermus thermophilus 70S ribosome in complex with triphenylphosphonium analog of chloramphenicol CAM-C4-TPP and protein Y (YfiA) at 2.80A resolution

SM: ARG ARG YXM YXM

Structure of complex 7mdz

7mdz

80S rabbit ribosome stalled with benzamide-CHX

SM: Z2V

Structure of complex 7mjv

7mjv

MiaB in the complex with s-adenosylmethionine and RNA

SM: SAM

Structure of complex 7mjw

7mjw

Methylated MiaB in the complex with 5'-deoxyadenosine, methionine and RNA

SM: 5AD 5AD ZKP ZKP

Structure of complex 7mjx

7mjx

MiaB in the complex with 5'-deoxyadenosine, methionine and RNA

SM: 5AD 5AD

Structure of complex 7n1p

7n1p

Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation

SM: ATP ATP ATP

Structure of complex 7n2c

7n2c

Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2)

SM: ATP ATP FUA

Structure of complex 7n2u

7n2u

Elongating 70S ribosome complex in a hybrid-H1 pre-translocation (PRE-H1) conformation

SM: ATP ATP

Structure of complex 7n2v

7n2v

Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1)

SM: ATP ATP GTP SCM SCM SCM

Structure of complex 7n30

7n30

Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation

SM: ATP ATP

Structure of complex 7n31

7n31

Elongating 70S ribosome complex in a post-translocation (POST) conformation

SM: ATP ATP

Structure of complex 7n8b

7n8b

Cycloheximide bound vacant 80S structure isolated from cbf5-D95A

SM: 3HE

Structure of complex 7nac

7nac

State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model

SM: SAH

Structure of complex 7naf

7naf

State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model

SM: SAH

Structure of complex 7nqh

7nqh

55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet

SM: 5GP 5GP SPM SPM SPM

Structure of complex 7nql

7nql

55S mammalian mitochondrial ribosome with ICT1 and P site tRNAMet

SM: 5GP 5GP SPM SPM SPM

Structure of complex 7nsh

7nsh

39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2

SM: 5GP 5GP SPM SPM

Structure of complex 7nsi

7nsi

55S mammalian mitochondrial ribosome with mtRRF (pre) and tRNA(P/E)

SM: 5GP SPM SPM SPM

Structure of complex 7nsj

7nsj

55S mammalian mitochondrial ribosome with tRNA(P/P) and tRNA(E*)

SM: 5GP SPM SPM SPM

Structure of complex 7nso

7nso

Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA

SM: ERY

Structure of complex 7nsp

7nsp

Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA

SM: ERY

Structure of complex 7nsq

7nsq

Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA

SM: TEL

Structure of complex 7nwg

7nwg

Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.

SM: BLS

Structure of complex 7nwi

7nwi

Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S

SM: BLS

Structure of complex 7o19

7o19

Cryo-EM structure of an Escherichia coli TnaC-ribosome complex stalled in response to L-tryptophan

SM: TRP

Structure of complex 7o1a

7o1a

Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome complex stalled in response to L-tryptophan

SM: TRP

Structure of complex 7o1c

7o1c

Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome-RF2 complex stalled in response to L-tryptophan

SM: TRP