Complex 7ctt
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.20 |
| System mass | 179.55 kDa |
| Deposition year | 2020 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Betacoronavirus |
| RCSB PDB Entry | 7ctt |
| Reference | Peng Qi, Peng Ruchao, Yuan Bin, Wang Min, Zhao Jingru, Fu Lifeng, Qi Jianxun, Shi Yi. 2021. Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir The Innovation |
| Equivalence Class |
NR_all_68817.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GE6 |
| Residue | . / 1004 |
| Chain | J / A |
| Non-redundant | True |
| Interacting RNA chains | E/Q, F/T |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | E/Q: unknown, F/T: unknown |
| RNA family global | unknown |
| Volume | 387.59 Å3 |
| Hydrophobicity | 0.372 |
| Hydrophilicity | 1.488 |
| Buriedness | 0.858 |
| Don/acc character | 0.571 |
| SiteScore | 1.050 |
| D Score | 0.896 |
| Kd | — |