Complex 7l6r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.98 |
| System mass | 52.47 kDa |
| Deposition year | 2020 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7l6r |
| Reference | Minasov George, Rosas-Lemus Monica, Shuvalova Ludmilla, Inniss Nicole L., Brunzelle Joseph S., Daczkowski Courtney M., Hoover Paul, Mesecar Andrew D., Satchell Karla J. F.. 2021. Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16 Science Signaling |
| Equivalence Class |
NR_all_11762.6
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAH |
| Residue | . / 7105 |
| Chain | H / A |
| Non-redundant | False |
| Interacting RNA chains | C/C |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | C/C: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 215.06 Å3 |
| Hydrophobicity | 0.813 |
| Hydrophilicity | 1.262 |
| Buriedness | 0.787 |
| Don/acc character | 1.137 |
| SiteScore | 1.060 |
| D Score | 1.001 |
| Kd | — |