Complex 7nsh
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.20 |
| System mass | 2021.11 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Sus |
| RCSB PDB Entry | 7nsh |
| Reference | Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad. 2021. Structural basis of translation termination, rescue, and recycling in mammalian mitochondria Molecular Cell |
| Equivalence Class |
NR_all_24610.5
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 5GP |
| Residue | . / 3206 |
| Chain | NJ / BA |
| Non-redundant | True |
| Interacting RNA chains | HA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | HA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 335.80 Å3 |
| Hydrophobicity | 0.172 |
| Hydrophilicity | 1.009 |
| Buriedness | 0.656 |
| Don/acc character | 2.430 |
| SiteScore | 1.110 |
| D Score | 0.981 |
| Kd | — |
| Compound | 5GP |
| Residue | . / 3207 |
| Chain | OJ / BA |
| Non-redundant | True |
| Interacting RNA chains | HA/BA |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | HA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 289.84 Å3 |
| Hydrophobicity | 0.473 |
| Hydrophilicity | 1.409 |
| Buriedness | 0.620 |
| Don/acc character | 0.604 |
| SiteScore | 1.098 |
| D Score | 0.853 |
| Kd | — |
| Compound | SPM |
| Residue | . / 3208 |
| Chain | PJ / BA |
| Non-redundant | True |
| Interacting RNA chains | HA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | HA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 665.08 Å3 |
| Hydrophobicity | 0.190 |
| Hydrophilicity | 1.169 |
| Buriedness | 0.783 |
| Don/acc character | 1.755 |
| SiteScore | 1.057 |
| D Score | 1.029 |
| Kd | — |
| Compound | SPM |
| Residue | . / 3209 |
| Chain | QJ / BA |
| Non-redundant | True |
| Interacting RNA chains | HA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | HA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 517.93 Å3 |
| Hydrophobicity | 0.201 |
| Hydrophilicity | 1.144 |
| Buriedness | 0.763 |
| Don/acc character | 1.001 |
| SiteScore | 1.043 |
| D Score | 1.025 |
| Kd | — |