Complex 7dwh
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.10 |
| System mass | 76.81 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7dwh |
| Reference | Jiang Hengyi, Gao Yanqing, Zhang Lei, Chen Dongrong, Gan Jianhua, Murchie Alastair I. H.. 2021. The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences Nature Catalysis |
| Equivalence Class |
NR_all_56532.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAM |
| Residue | . / 102 |
| Chain | H / X |
| Non-redundant | True |
| Interacting RNA chains | E/X |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | E/X: ribozyme |
| RNA family global | ribozyme |
| Volume | 251.76 Å3 |
| Hydrophobicity | 0.163 |
| Hydrophilicity | 0.869 |
| Buriedness | 0.638 |
| Don/acc character | 4.472 |
| SiteScore | 0.939 |
| D Score | 0.777 |
| Kd | — |
| Compound | SAM |
| Residue | . / 102 |
| Chain | J / Y |
| Non-redundant | True |
| Interacting RNA chains | F/Y |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | F/Y: ribozyme |
| RNA family global | ribozyme |
| Volume | 163.61 Å3 |
| Hydrophobicity | 0.337 |
| Hydrophilicity | 0.811 |
| Buriedness | 0.628 |
| Don/acc character | 3.372 |
| SiteScore | 0.848 |
| D Score | 0.668 |
| Kd | — |