Complex 7aap
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.50 |
| System mass | 181.60 kDa |
| Deposition year | 2020 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Betacoronavirus |
| RCSB PDB Entry | 7aap |
| Reference | Naydenova Katerina, Muir Kyle W., Wu Long-Fei, Zhang Ziguo, Coscia Francesca, Peet Mathew J., Castro-Hartmann Pablo, Qian Pu, Sader Kasim, Dent Kyle, Kimanius Dari, Sutherland John D., Löwe Jan, Barford David, Russo Christopher J.. 2021. Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_59092.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GE6 |
| Residue | . / 1601 |
| Chain | M / T |
| Non-redundant | True |
| Interacting RNA chains | F/T, E/P |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/P: unknown, F/T: unknown |
| RNA family global | unknown |
| Volume | 245.25 Å3 |
| Hydrophobicity | 0.553 |
| Hydrophilicity | 1.224 |
| Buriedness | 0.866 |
| Don/acc character | 0.863 |
| SiteScore | 0.801 |
| D Score | 0.661 |
| Kd | — |