Complex 7naf
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.13 |
| System mass | 311.69 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Saccharomyces |
| RCSB PDB Entry | 7naf |
| Reference | Cruz Victor Emmanuel, Sekulski Kamil, Peddada Nagesh, Sailer Carolin, Balasubramanian Sahana, Weirich Christine S., Stengel Florian, Erzberger Jan P.. 2022. Sequence-specific remodeling of a topologically complex RNP substrate by Spb4 Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_36824.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAH |
| Residue | . / 801 |
| Chain | Q / w |
| Non-redundant | True |
| Interacting RNA chains | A/1 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/1: rRNA |
| RNA family global | rRNA |
| Volume | 273.37 Å3 |
| Hydrophobicity | 0.831 |
| Hydrophilicity | 1.208 |
| Buriedness | 0.823 |
| Don/acc character | 0.531 |
| SiteScore | 1.084 |
| D Score | 1.040 |
| Kd | — |