Harnessing RIBOnucleic acid - Small molecules Structures
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolide erythromycin, mRNA, deacylated A-site tRNAphe, P-site fMRC-peptidyl-tRNAmet, and deacylated E-site tRNAphe at 2.75A resolution
SM: ERY
Human 80S ribosome bound to IDB-001 stalled on MYC nascent chain
SM: A1B75
Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chain
SM: A1B76
Membrane-associated human mitoribosome in complex with TACO1
SM: NAD SPM
Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
SM: SAH
In situ human P-Z state 80S ribosome
SM: SPM
In situ human P-E state 80S ribosome
In situ human eEF2-A/P-P/E state 80S ribosome
In situ human eEF1A-A/T-P state 80S ribosome
In situ human Hibernating rotate 3 with E-site tRNA state 80S ribosome
In situ human Hibernating rotate3 with Z site tRNA state 80S ribosome
In situ human hibernating class2 80S ribosome
In situ human Hibernating class3 80S ribosome
In situ human Hibernating class4 80S ribosome
In situ human Hibernating class5 80S ribosome
In situ HHT and CHX treated A-P state 80S ribosome
SM: HMT SPM
In situ HHT and CHX treated A-P-Z state 80S ribosome
In situ HHT and CHX treated human eEF1A-A/T-P state 80S ribosome
SM: 3HE HMT SPM
In situ HHT and CHX treated human eEF1A-A/T-P-Z state 80S ribosome
In situ HHT and CHX treated human P state 80S ribosome
In situ human post eEF1A-A/T-P-E state 80S ribosome
In situ human Post-eEF1A-AT-P state 80S ribosome
In situ human Post-eEF1A-A/T-P-Z state 80S ribosome
In situ human AT-P-Z state ribosome
In situ human A-P state 80S ribosome
In situ human A-P-Z state 80S ribosome
In situ human A-P-E state 80S ribosome
In situ human eEF1A-A/T-P-E state 80S ribosome
In situ human Hibernating class1 (rotate3) without E tRNA state 80S ribosome
In situ human A/P-P/E state 80S ribosome
In situ HHT and CHX treated human P-Z state 80S ribosome
In situ human unrotated hibernating with CCDC124 state 80S ribosome
In situ human unrotated hibernating without CCDC124 state 80S ribosome
In situ human 60S ribosome
In situ human 60S ribosome with EIF6
In situ human 80S consensus ribosome with EBP1
In situ human 80S ribosome (composite map)
Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in NTP-bound elongation state
SM: ZAN
Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in pre-reaction elongation state
In situ structure of the human mitoribosome in the P-E state
In situ structure of the human mitoribosome in the P state
In situ structure of the human mitoribosome in the A-P-E state with TACO1
In situ structure of the human mitoribosome in the A-P state with TACO1
In situ structure of the human mitoribosome in the P-E state from TACO1-knockout cells
In situ HHT and CHX treated human hibernating state 80S ribosome
In situ CHX and HHT treated 80S consensus ribosome
In situ human P state 80S ribosome
In situ structure of the human mitoribosome in the P state from TACO1-knockout cells
In situ structure of human mitoribosome in the A/T-P state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A-P state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/P-P/E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/T-P-E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A-P-E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/P-P/E state
RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GTP bound in E-site.
SM: 8GT
SARS-CoV-2 core polymerase complex bound to RNA, araUMP, and UTP
SM: UTP
Cryo-EM structure of the 70S ribosome of a MLSb sensitive S. aureus strain "KES34" in complex with solithromycin
SM: EM1
Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin
Ternary complex of translating ribosome, NAC and NMT1
Quaternary complex of a translating ribosome, NAC, NMT1, and NatA
Current selection range: to