Complex 9o3h
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.65 |
| System mass | 4571.80 kDa |
| Deposition year | 2025 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 9o3h |
| Reference | Syroegin Egor A., Aleksandrova Elena V., Kruglov Artem A., Paranjpe Madhura N., Svetlov Maxim S., Polikanov Yury S.. 2025. Structural insights into context-specific inhibition of bacterial translation by macrolides preprint (bioRxiv) |
| Equivalence Class |
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ERY |
| Residue | . / 4104 |
| Chain | VTA / 1A |
| Non-redundant | True |
| Interacting RNA chains | A/1A |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/1A: rRNA |
| RNA family global | rRNA |
| Volume | 155.04 Å3 |
| Hydrophobicity | 0.190 |
| Hydrophilicity | 0.924 |
| Buriedness | 0.546 |
| Don/acc character | 0.980 |
| SiteScore | 0.801 |
| D Score | 0.813 |
| Kd | — |
| Compound | ERY |
| Residue | . / 3859 |
| Chain | BSC / 2A |
| Non-redundant | True |
| Interacting RNA chains | FB/2A |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | FB/2A: rRNA |
| RNA family global | rRNA |
| Volume | 201.68 Å3 |
| Hydrophobicity | 0.371 |
| Hydrophilicity | 0.904 |
| Buriedness | 0.604 |
| Don/acc character | 1.181 |
| SiteScore | 0.934 |
| D Score | 0.970 |
| Kd | — |