HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9pgi

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.02
System mass 3162.09 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9pgi
Reference Wang Shuhui, Brischigliaro Michele, Zhang Yuekang, Wu Chunxiang, Zheng Wei, Barrientos Antoni, Xiong Yong. 2026. Structural basis of TACO1-mediated efficient mitochondrial translation Nature Communications
Equivalence Class NR_all_93855.32
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound NAD
Residue . / 1701
Chain ZJ / AA
Non-redundant True
Interacting RNA chains EC/AA
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains EC/AA: rRNA
RNA family global rRNA
Volume 884.25 Å3
Hydrophobicity 0.145
Hydrophilicity 1.537
Buriedness 0.820
Don/acc character 0.705
SiteScore 1.082
D Score 0.931
Kd

Compound SPM
Residue . / 1702
Chain AK / AA
Non-redundant True
Interacting RNA chains EC/AA
RNA environment detailled ion
RNA environment global RNA
RNA family chains EC/AA: rRNA
RNA family global rRNA
Volume 787.53 Å3
Hydrophobicity 0.160
Hydrophilicity 1.152
Buriedness 0.805
Don/acc character 3.324
SiteScore 1.221
D Score 1.047
Kd

Compound SPM
Residue . / 1781
Chain BN / AA
Non-redundant True
Interacting RNA chains EC/AA
RNA environment detailled ion
RNA environment global RNA
RNA family chains EC/AA: rRNA
RNA family global rRNA
Volume 237.36 Å3
Hydrophobicity 0.254
Hydrophilicity 0.998
Buriedness 0.725
Don/acc character 4.371
SiteScore 0.842
D Score 0.598
Kd