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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9muj

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SAH
Residue . / 301
Chain D / A
Non-redundant True
Interacting RNA chains C/C
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains C/C: rRNA
RNA family global rRNA
Volume 178.36 Å3
Hydrophobicity 1.164
Hydrophilicity 0.820
Buriedness 0.784
Don/acc character 1.100
SiteScore 1.100
D Score 1.143
Kd