Harnessing RIBOnucleic acid - Small molecules Structures
Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
SM: AMP
SAM-I riboswitch bearing the H. marismortui Kt-7 variant C-2bU
SM: SAM
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UG
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is GG
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CC
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UU
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is AA
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CA
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UA
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is GU
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UC
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CG
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CU
Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A
SM: 3HE
Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates
SM: SAH
Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates
Crystal structure of box C/D RNP with 13 nt guide regions and 11 nt substrates
Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome
SM: GDP
RNA primer-template complex with 2-methylimidazole-activated monomer analogue
SM: PZG
RNA primer-template complex with 2-methylimidazole-activated monomer analogue-2 binding sites
RNA primer-template complex with 2-methylimidazole-activated monomer analogue-3 binding sites
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin
SM: 3QB
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin
SM: 62B EPE
Crystal structure of Amicoumacin A bound to the yeast 80S ribosome
SM: UAM
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin
SM: PAR SPE
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
SM: SPE
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site
Structure of RelA bound to the 70S ribosome
SM: PAR
Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2
SM: GCP
High-resolution structure of the Escherichia coli ribosome
SM: 1PE PG4
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic
SM: 6EK
Structure of the WT E coli ribosome bound to tetracycline
SM: 1PE PG4 TAC
Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline
SM: 1PE PG4 T1C
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
Structure of the Wild-type 70S E coli ribosome bound to Tigecycline
Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA
SM: ERY
Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)
Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU
SM: UTP
Structure of a 5-hydroxytryptophan aptamer
SM: 4PQ
RNA 15mer duplex binding with PZG monomer
Selective Small Molecule Inhibition of the FMN Riboswitch
SM: 6YG
Self-complimentary RNA 15mer binding with GMP monomers
SM: 5GP
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
Structure of bacterial 30S-IF1-IF2-IF3-mRNA-tRNA translation pre-initiation complex(state-III)
SM: FME
Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa.
SM: GTP
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
SM: GNP
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Nonstop ribosomal complex bound with Dom34 and Hbs1
Crystal structure of Agelastatin A bound to the 80S ribosome
SM: 7MB
Crystal structure of geneticin (G418) bound to the yeast 80S ribosome
SM: GET
Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)
SM: 8UZ
Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA
Crystal structure of Paromomycin bound to the yeast 80S ribosome
Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome
Current selection range: to
