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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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2077 RNA-SM complexes found
Structure of complex 5l00

5l00

Self-complimentary RNA 15mer binding with GMP monomers

SM: 5GP 5GP 5GP 5GP

Structure of complex 5lks

5lks

Structure-function insights reveal the human ribosome as a cancer target for antibiotics

SM: 3HE

Structure of complex 5lmv

5lmv

Structure of bacterial 30S-IF1-IF2-IF3-mRNA-tRNA translation pre-initiation complex(state-III)

SM: FME

Structure of complex 5lwj

5lwj

Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa.

SM: GTP

Structure of complex 5lzd

5lzd

Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)

SM: GNP

Structure of complex 5lzs

5lzs

Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

SM: GDP

Structure of complex 5lzw

5lzw

Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.

SM: GCP

Structure of complex 5m1j

5m1j

Nonstop ribosomal complex bound with Dom34 and Hbs1

SM: GNP

Structure of complex 5mei

5mei

Crystal structure of Agelastatin A bound to the 80S ribosome

SM: 7MB 7MB

Structure of complex 5ndg

5ndg

Crystal structure of geneticin (G418) bound to the yeast 80S ribosome

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET

Structure of complex 5ndj

5ndj

Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndk

5ndk

Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA

SM: 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndv

5ndv

Structure of complex 5ndw

5ndw

Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5nrg

5nrg

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

SM: 95H EPE

Structure of complex 5ns4

5ns4

Crystal structures of Cy3 cyanine fluorophores stacked onto the end of double-stranded RNA

SM: 96T

Structure of complex 5o61

5o61

The complete structure of the Mycobacterium smegmatis 70S ribosome

SM: PHE

Structure of complex 5ob3

5ob3

iSpinach aptamer

SM: 1TU SPM

Structure of complex 5obm

5obm

Crystal structure of Gentamicin bound to the yeast 80S ribosome

SM: LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL

Structure of complex 5omw

5omw

Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on2

5on2

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on3

5on3

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on6

5on6

Crystal structure of haemanthamine bound to the 80S ribosome

SM: HN8 HN8

Structure of complex 5onh

5onh

Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5ot7

5ot7

Elongation factor G-ribosome complex captures in the absence of inhibitors.

SM: GDP

Structure of complex 5t83

5t83

Structure of a guanidine-I riboswitch from S. acidophilus

SM: SPK

Structure of complex 5tbw

5tbw

Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome

SM: 7AL 7AL

Structure of complex 5tcu

5tcu

Methicillin sensitive Staphylococcus aureus 70S ribosome

SM: PAR

Structure of complex 5tgm

5tgm

Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro

SM: PHE PHE SPS SPS

Structure of complex 5ued

5ued

RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G

SM: 86S 86S

Structure of complex 5uee

5uee

RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 5ueg

5ueg

RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand

SM: 86P 86P 86P 86P

Structure of complex 5uh6

5uh6

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin

SM: RFP

Structure of complex 5uhc

5uhc

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin

SM: RFP

Structure of complex 5uj2

5uj2

Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

SM: 8B4

Structure of complex 5umd

5umd

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

SM: YMZ YMZ

Structure of complex 5ux3

5ux3

RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue

SM: 8OS

Structure of complex 5uyl

5uyl

70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)

SM: FME

Structure of complex 5uym

5uym

70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)

SM: FME

Structure of complex 5uyp

5uyp

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)

SM: FME

Structure of complex 5uyq

5uyq

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)

SM: FME

Structure of complex 5v0h

5v0h

RNA duplex with 2-MeImpG analogue bound-one binding site

SM: 8OS 8OS

Structure of complex 5v0j

5v0j

RNA duplex with 2-MeImpG analogue bound-2 binding sites

SM: 8OS 8OS 8OS 8OS

Structure of complex 5v0k

5v0k

RNA duplex with 2-MeImpG analogue bound-3 binding sites

SM: 8OS 8OS

Structure of complex 5v0o

5v0o

RNA hairpin structure containing 2-MeImpG analogue bound

SM: 8OS

Structure of complex 5v1l

5v1l

Structure of S-GNA dodecamer

SM: SPM

Structure of complex 5v3f

5v3f

Co-crystal structure of the fluorogenic RNA Mango

SM: 74G 74G

Structure of complex 5v7q

5v7q

Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog

SM: 917

Structure of complex 5v8i

5v8i

Thermus thermophilus 70S ribosome lacking ribosomal protein uS17

SM: ARG ARG

Structure of complex 5v9z

5v9z

RNA hairpin structure containing 2-MeImpG analogue bound

SM: 8OS

Structure of complex 5vcf

5vcf

RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue

SM: 8OS

Structure of complex 5vci

5vci

RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue

SM: 8OS

Structure of complex 5vj9

5vj9

Guanidine-II riboswitch P2 hairpin dimer from Pseudomonas aeruginosa

SM: SPM SPM SPM SPM SPM

Structure of complex 5vjb

5vjb

Guanidine-II riboswitch P2 hairpin dimer with 5-bromoU substitution from Pseudomonas aeruginosa

SM: SPM SPM SPM SPM

Structure of complex 5vp2

5vp2

Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution

SM: M2D M2D

Structure of complex 5vw1

5vw1

Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex

SM: PG4

Structure of complex 5w0o

5w0o

Structure of human TUT7 catalytic module (CM) in complex with dsRNA

SM: UTP UTP

Structure of complex 5w51

5w51

Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP

SM: 2KH

Structure of complex 5wdt

5wdt

70S ribosome-EF-Tu H84A complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we4

5we4

70S ribosome-EF-Tu wt complex with GppNHp

SM: FME GNP PHE