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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 5ndv

5ndv

Structure of complex 5ndw

5ndw

Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5nrg

5nrg

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

SM: 95H EPE

Structure of complex 5ns4

5ns4

Crystal structures of Cy3 cyanine fluorophores stacked onto the end of double-stranded RNA

SM: 96T

Structure of complex 5o61

5o61

The complete structure of the Mycobacterium smegmatis 70S ribosome

SM: PHE

Structure of complex 5obm

5obm

Crystal structure of Gentamicin bound to the yeast 80S ribosome

SM: LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL

Structure of complex 5omw

5omw

Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on2

5on2

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on3

5on3

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on6

5on6

Crystal structure of haemanthamine bound to the 80S ribosome

SM: HN8 HN8

Structure of complex 5onh

5onh

Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5ot7

5ot7

Elongation factor G-ribosome complex captures in the absence of inhibitors.

SM: GDP

Structure of complex 5tbw

5tbw

Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome

SM: 7AL 7AL

Structure of complex 5tcu

5tcu

Methicillin sensitive Staphylococcus aureus 70S ribosome

SM: PAR

Structure of complex 5tgm

5tgm

Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro

SM: PHE PHE SPS SPS

Structure of complex 5uj2

5uj2

Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

SM: 8B4

Structure of complex 5umd

5umd

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

SM: YMZ YMZ

Structure of complex 5uyl

5uyl

70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)

SM: FME

Structure of complex 5uym

5uym

70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)

SM: FME

Structure of complex 5uyp

5uyp

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)

SM: FME

Structure of complex 5uyq

5uyq

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)

SM: FME

Structure of complex 5v7q

5v7q

Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog

SM: 917

Structure of complex 5v8i

5v8i

Thermus thermophilus 70S ribosome lacking ribosomal protein uS17

SM: ARG ARG

Structure of complex 5vp2

5vp2

Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution

SM: M2D M2D

Structure of complex 5vw1

5vw1

Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex

SM: PG4

Structure of complex 5w0o

5w0o

Structure of human TUT7 catalytic module (CM) in complex with dsRNA

SM: UTP UTP

Structure of complex 5wdt

5wdt

70S ribosome-EF-Tu H84A complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we4

5we4

70S ribosome-EF-Tu wt complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we6

5we6

70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA

SM: FME PHE

Structure of complex 5wf0

5wf0

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)

SM: FME PHE

Structure of complex 5wfk

5wfk

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)

SM: FME PHE

Structure of complex 5wfs

5wfs

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)

SM: FME GTP PHE

Structure of complex 5wis

5wis

Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution

SM: MT9 MT9

Structure of complex 5wit

5wit

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution

SM: AQJ AQJ

Structure of complex 5wnt

5wnt

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: B6M

Structure of complex 5wnu

5wnu

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: B6M

Structure of complex 5wnv

5wnv

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: B6M

Structure of complex 5wwr

5wwr

Crystal structure of human NSun6/tRNA/SFG

SM: SFG SFG

Structure of complex 5wws

5wws

Crystal structure of human NSun6/tRNA/SAM

SM: SAM SAM

Structure of complex 5zc9

5zc9

Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex

SM: RCG

Structure of complex 5zq0

5zq0

Crystal structure of spRlmCD with U747loop RNA

SM: SAH

Structure of complex 6aax

6aax

Crystal structure of TFB1M and h45 with SAM in homo sapiens

SM: SAM

Structure of complex 6az1

6az1

Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin

SM: PAR PAR PAR PAR PAR

Structure of complex 6az3

6az3

Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin

SM: PAR PAR PAR PAR PAR PAR PAR PAR PAR

Structure of complex 6b4v

6b4v

Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6bjy

6bjy

VSV Nucleocapsid with Polyamide Bound

SM: DV4

Structure of complex 6boh

6boh

Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6cao

6cao

Structure of the ribosomal decoding complex at ambient temperature

SM: PAR PAR PAR PAR PAR

Structure of complex 6cap

6cap

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin

SM: SIS

Structure of complex 6caq

6caq

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: EUS

Structure of complex 6car

6car

Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin

SM: SIS

Structure of complex 6cas

6cas

Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with N1MS

SM: EUS

Structure of complex 6cfj

6cfj

Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound to mRNA and A-, P-, and E-site tRNAs at 2.8A resolution

SM: EZG EZG

Structure of complex 6cfk

6cfk

Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution

SM: ARG ARG EZP EZP

Structure of complex 6cfl

6cfl

Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution

SM: ARG ARG EZM EZM

Structure of complex 6czr

6czr

The structure of amicetin bound to the 70S ribosome

SM: ARG ARG FSD FSD

Structure of complex 6db8

6db8

Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer

SM: G4A

Structure of complex 6ddd

6ddd

Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-5

SM: G6V

Structure of complex 6ddg

6ddg

Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6

SM: G6M

Structure of complex 6dtd

6dtd

High-resolution crystal structure of Cas13b from Prevotella buccae

SM: CIT PG4 PG4