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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 4v8u

4v8u

Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex.

SM: FUA FUA

Structure of complex 4v97

4v97

Crystal structure of the bacterial ribosome ram mutation G299A.

SM: PAR PAR

Structure of complex 4v9a

4v9a

Crystal Structure of the 70S ribosome with tetracycline.

SM: TAC TAC

Structure of complex 4v9b

4v9b

Crystal Structure of the 70S ribosome with tigecycline.

SM: T1C T1C

Structure of complex 4v9c

4v9c

Allosteric control of the ribosome by small-molecule antibiotics

SM: NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY

Structure of complex 4v9h

4v9h

Crystal structure of the ribosome bound to elongation factor G in the guanosine triphosphatase state

SM: GCP

Structure of complex 4v9l

4v9l

70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.

SM: GDP

Structure of complex 4v9m

4v9m

70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.

SM: FUA FUA

Structure of complex 4v9p

4v9p

Control of ribosomal subunit rotation by elongation factor G

SM: GCP

Structure of complex 4v9q

4v9q

Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.

SM: BLS BLS

Structure of complex 4w29

4w29

70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state.

SM: FUA FUA NMY NMY NMY NMY NMY NMY

Structure of complex 4w2f

4w2f

Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites

SM: UAM UAM

Structure of complex 4w2g

4w2g

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites

SM: PCY PCY

Structure of complex 4w2h

4w2h

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site

SM: PCY PCY

Structure of complex 4w2i

4w2i

Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites

SM: NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG

Structure of complex 4w90

4w90

Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO

SM: 2BA 2BA

Structure of complex 4w92

4w92

Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO

SM: 2BA 2BA

Structure of complex 4wc2

4wc2

Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog

SM: APC

Structure of complex 4wc6

4wc6

Structure of tRNA-processing enzyme complex 4

SM: ATP

Structure of complex 4wc7

4wc7

Structure of tRNA-processing enzyme complex 5

SM: CTP

Structure of complex 4wce

4wce

The crystal structure of the large ribosomal subunit of Staphylococcus aureus

SM: EPE

Structure of complex 4wf1

4wf1

Crystal structure of the E. coli ribosome bound to negamycin.

SM: NEG

Structure of complex 4wf9

4wf9

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with telithromycin

SM: TEL

Structure of complex 4wfa

4wfa

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid

SM: EPE EPE EPE EPE ZLD

Structure of complex 4wfb

4wfb

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with BC-3205

SM: 3LK EPE EPE EPE EPE

Structure of complex 4wfn

4wfn

Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin

SM: ERY

Structure of complex 4woi

4woi

4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2

SM: PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR

Structure of complex 4wpo

4wpo

Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state

SM: GDP

Structure of complex 4wqf

4wqf

Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G and fusidic acid in the post-translocational state

SM: FUA FUA

Structure of complex 4wqy

4wqy

Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid)

SM: GDP

Structure of complex 4wra

4wra

Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin.

SM: PAR PAR

Structure of complex 4wsd

4wsd

Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site and with antibiotic paromomycin.

SM: PAR PAR

Structure of complex 4wt8

4wt8

Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex

SM: 3V6 3V6 PAR PAR

Structure of complex 4wta

4wta

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH UDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

SM: UDP

Structure of complex 4wtc

4wtc

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH CDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AGAAAUUU

SM: CDP

Structure of complex 4wtd

4wtd

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH ADP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AUAAAUUU

SM: ADP

Structure of complex 4wte

4wte

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-ACAAAUUU

SM: GDP

Structure of complex 4wtf

4wtf

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GS-639475, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

SM: 5GS

Structure of complex 4wtg

4wtg

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH SOFOSBUVIR DIPHOSPHATE GS-607596, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

SM: 6GS

Structure of complex 4wti

4wti

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-ACGG, RNA PRIMER 5'-PCC, MN2+, AND GDP

SM: GDP

Structure of complex 4wtj

4wtj

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-AUCC, RNA PRIMER 5'-PGG, MN2+, AND ADP

SM: ADP

Structure of complex 4wtk

4wtk

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-AGCC, RNA PRIMER 5'-PGG, MN2+, AND CDP

SM: CDP

Structure of complex 4wtl

4wtl

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-UACC, RNA PRIMER 5'-PGG, MN2+, AND UDP

SM: UDP

Structure of complex 4wtm

4wtm

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-UAGG, RNA PRIMER 5'-PCC, MN2+, AND UDP

SM: UDP

Structure of complex 4www

4www

Crystal structure of the E. coli ribosome bound to CEM-101

SM: EM1

Structure of complex 4x4n

4x4n

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix

SM: 5GP GMP

Structure of complex 4x4o

4x4o

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix and CTP

SM: CTP

Structure of complex 4x4q

4x4q

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCAC and CTP

SM: CTP CTP

Structure of complex 4x4r

4x4r

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and AMPcPP

SM: APC APC

Structure of complex 4x4s

4x4s

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and CTP

SM: CTP CTP

Structure of complex 4x4u

4x4u

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a human MenBeta minihelix ending in CCACC

SM: APC APC

Structure of complex 4x4v

4x4v

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a human MenBeta minihelix ending in CCACC and AMPcPP

SM: 5GP 5GP 5GP APC APC

Structure of complex 4x62

4x62

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 4x64

4x64

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 4x65

4x65

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 4x66

4x66

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 4y4o

4y4o

Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution

SM: ARG ARG

Structure of complex 4yb1

4yb1

20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP

SM: 4BW

Structure of complex 4ybb

4ybb

High-resolution structure of the Escherichia coli ribosome

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 4yco

4yco

E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe

SM: FMN FMN FMN