Complex 4w29
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.80 |
| System mass | 4630.82 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4w29 |
| Reference | Zhou Jie, Lancaster Laura, Donohue John Paul, Noller Harry F.. 2014. How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation Science |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | FUA |
| Residue | . / 702 |
| Chain | TD / AY |
| Non-redundant | True |
| Interacting RNA chains | HB/BA |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | HB/BA: rRNA |
| RNA family global | rRNA |
| Volume | 214.38 Å3 |
| Hydrophobicity | 1.357 |
| Hydrophilicity | 0.998 |
| Buriedness | 0.815 |
| Don/acc character | 1.015 |
| SiteScore | 0.903 |
| D Score | 0.867 |
| Kd | — |
| Compound | FUA |
| Residue | . / 702 |
| Chain | AE / CY |
| Non-redundant | True |
| Interacting RNA chains | QD/DA |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | QD/DA: rRNA |
| RNA family global | rRNA |
| Volume | 204.43 Å3 |
| Hydrophobicity | 0.952 |
| Hydrophilicity | 0.918 |
| Buriedness | 0.776 |
| Don/acc character | 0.964 |
| SiteScore | 0.866 |
| D Score | 0.838 |
| Kd | — |
| Compound | NMY |
| Residue | . / 1601 |
| Chain | UD / AA |
| Non-redundant | True |
| Interacting RNA chains | U/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | U/AA: rRNA |
| RNA family global | rRNA |
| Volume | 170.81 Å3 |
| Hydrophobicity | 0.348 |
| Hydrophilicity | 0.668 |
| Buriedness | 0.707 |
| Don/acc character | 3.181 |
| SiteScore | 0.609 |
| D Score | 0.546 |
| Kd | — |
| Compound | NMY |
| Residue | . / 2902 |
| Chain | WD / BA |
| Non-redundant | True |
| Interacting RNA chains | HB/BA, U/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | U/AA: rRNA, HB/BA: rRNA |
| RNA family global | rRNA |
| Volume | 170.81 Å3 |
| Hydrophobicity | 0.457 |
| Hydrophilicity | 0.804 |
| Buriedness | 0.688 |
| Don/acc character | 1.261 |
| SiteScore | 0.800 |
| D Score | 0.592 |
| Kd | — |
| Compound | NMY |
| Residue | . / 2903 |
| Chain | XD / BA |
| Non-redundant | True |
| Interacting RNA chains | HB/BA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | HB/BA: rRNA |
| RNA family global | rRNA |
| Volume | 62.77 Å3 |
| Hydrophobicity | 0.032 |
| Hydrophilicity | 0.896 |
| Buriedness | 0.564 |
| Don/acc character | 4.417 |
| SiteScore | 0.609 |
| D Score | 0.372 |
| Kd | — |
| Compound | NMY |
| Residue | . / 2904 |
| Chain | YD / BA |
| Non-redundant | True |
| Interacting RNA chains | HB/BA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | HB/BA: rRNA |
| RNA family global | rRNA |
| Volume | 588.93 Å3 |
| Hydrophobicity | 0.271 |
| Hydrophilicity | 1.104 |
| Buriedness | 0.802 |
| Don/acc character | 2.343 |
| SiteScore | 1.220 |
| D Score | 1.061 |
| Kd | — |
| Compound | NMY |
| Residue | . / 1601 |
| Chain | CE / CA |
| Non-redundant | True |
| Interacting RNA chains | DC/CA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | DC/CA: rRNA |
| RNA family global | rRNA |
| Volume | 421.89 Å3 |
| Hydrophobicity | 0.176 |
| Hydrophilicity | 0.812 |
| Buriedness | 0.657 |
| Don/acc character | 1.321 |
| SiteScore | 0.960 |
| D Score | 0.996 |
| Kd | — |
| Compound | NMY |
| Residue | . / 2901 |
| Chain | DE / DA |
| Non-redundant | True |
| Interacting RNA chains | QD/DA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | QD/DA: rRNA |
| RNA family global | rRNA |
| Volume | 196.88 Å3 |
| Hydrophobicity | 0.111 |
| Hydrophilicity | 0.933 |
| Buriedness | 0.670 |
| Don/acc character | 1.919 |
| SiteScore | 0.827 |
| D Score | 0.621 |
| Kd | — |