Complex 4x4n
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.95 |
| System mass | 247.32 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 4x4n |
| Reference | Kuhn Claus-D., Wilusz Jeremy E., Zheng Yuxuan, Beal Peter A., Joshua-Tor Leemor. 2015. On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme Cell |
| Equivalence Class |
NR_all_51503.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 5GP |
| Residue | . / 102 |
| Chain | K / B |
| Non-redundant | True |
| Interacting RNA chains | C/B |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | C/B: tRNA |
| RNA family global | tRNA |
| Volume | 210.95 Å3 |
| Hydrophobicity | 0.109 |
| Hydrophilicity | 1.074 |
| Buriedness | 0.615 |
| Don/acc character | 0.991 |
| SiteScore | 0.735 |
| D Score | 0.691 |
| Kd | — |
| Compound | GMP |
| Residue | . / 101 |
| Chain | J / B |
| Non-redundant | True |
| Interacting RNA chains | C/B |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | C/B: tRNA |
| RNA family global | tRNA |
| Volume | 57.28 Å3 |
| Hydrophobicity | 0.030 |
| Hydrophilicity | 1.270 |
| Buriedness | 0.597 |
| Don/acc character | 0.585 |
| SiteScore | 0.559 |
| D Score | 0.405 |
| Kd | — |