Complex 4x4r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.20 |
| System mass | 133.47 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 4x4r |
| Reference | Kuhn Claus-D., Wilusz Jeremy E., Zheng Yuxuan, Beal Peter A., Joshua-Tor Leemor. 2015. On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme Cell |
| Equivalence Class |
NR_all_51503.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | APC |
| Residue | . / 501 |
| Chain | F / A |
| Non-redundant | True |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | B/B: tRNA |
| RNA family global | tRNA |
| Volume | 538.85 Å3 |
| Hydrophobicity | 0.043 |
| Hydrophilicity | 1.651 |
| Buriedness | 0.849 |
| Don/acc character | 0.673 |
| SiteScore | 1.101 |
| D Score | 0.911 |
| Kd | — |
| Compound | APC |
| Residue | . / 501 |
| Chain | K / C |
| Non-redundant | True |
| Interacting RNA chains | D/D |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | D/D: tRNA |
| RNA family global | tRNA |
| Volume | 619.12 Å3 |
| Hydrophobicity | 0.165 |
| Hydrophilicity | 1.395 |
| Buriedness | 0.826 |
| Don/acc character | 0.694 |
| SiteScore | 1.085 |
| D Score | 0.981 |
| Kd | — |