Complex 4wfa
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.39 |
| System mass | 1362.37 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Staphylococcus |
| RCSB PDB Entry | 4wfa |
| Reference | Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. 2015. Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_90633.30
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | EPE |
| Residue | . / 3423 |
| Chain | IQ / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 502.84 Å3 |
| Hydrophobicity | 0.082 |
| Hydrophilicity | 1.212 |
| Buriedness | 0.775 |
| Don/acc character | 1.868 |
| SiteScore | 0.992 |
| D Score | 0.741 |
| Kd | — |
| Compound | EPE |
| Residue | . / 3424 |
| Chain | JQ / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 260.68 Å3 |
| Hydrophobicity | 0.000 |
| Hydrophilicity | 1.576 |
| Buriedness | 0.808 |
| Don/acc character | 0.776 |
| SiteScore | 0.692 |
| D Score | 0.422 |
| Kd | — |
| Compound | EPE |
| Residue | . / 3425 |
| Chain | KQ / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 712.75 Å3 |
| Hydrophobicity | 0.033 |
| Hydrophilicity | 1.449 |
| Buriedness | 0.822 |
| Don/acc character | 1.943 |
| SiteScore | 1.233 |
| D Score | 0.961 |
| Kd | — |
| Compound | EPE |
| Residue | . / 3426 |
| Chain | LQ / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 410.23 Å3 |
| Hydrophobicity | 0.095 |
| Hydrophilicity | 1.786 |
| Buriedness | 0.919 |
| Don/acc character | 0.705 |
| SiteScore | 1.148 |
| D Score | 0.909 |
| Kd | — |
| Compound | ZLD |
| Residue | . / 3001 |
| Chain | CA / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 613.97 Å3 |
| Hydrophobicity | 0.278 |
| Hydrophilicity | 1.099 |
| Buriedness | 0.765 |
| Don/acc character | 2.137 |
| SiteScore | 1.195 |
| D Score | 1.040 |
| Kd | — |