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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 8vvr

8vvr

Post-decoding/Post-hydrolysis state obtained from Anisomycin-treated mammalian ribosomes

SM: ANM

Structure of complex 8vvs

8vvs

Post-decoding post-hydrolysis state obtained from merged datasets of elongation inhibitor-treated mammalian ribosomes

SM: ANM

Structure of complex 8vvt

8vvt

Mammalian ribosomes bound to Anisomycin in the rotated conformation

SM: ANM

Structure of complex 8vvu

8vvu

Anisomycin-bound mammalian ribosome with partially accommodated A-site tRNA

SM: ANM

Structure of complex 8xko

8xko

CryoEM structure of compound HNC-1664 bound with RdRP-RNA complex of SARS-CoV-2

SM: A1LVZ

Structure of complex 8xpo

8xpo

Cryo-EM structure of Lassa virus RdRP elongation complex with the NTP form of compound HNC-1664 bound in the active site

SM: A1LVZ

Structure of complex 8xsx

8xsx

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2

SM: T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsy

8xsy

Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)

SM: T1C T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsz

8xsz

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA

SM: T1C T1C T1C T1C T1C

Structure of complex 8xt0

8xt0

Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline

SM: T1C T1C T1C

Structure of complex 8xt1

8xt1

Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline

SM: T1C

Structure of complex 8xt2

8xt2

Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline

SM: T1C T1C T1C

Structure of complex 8xt3

8xt3

Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline

SM: T1C

Structure of complex 8xz3

8xz3

Mycobacterium smegmatis 50S ribosomal subunit with Erythromycin

SM: ERY

Structure of complex 8y2o

8y2o

The Cryo-EM structure of human tRNA methyltransferase FTSJ1-THADA with substrate tRNA and S-adenosyl homocysteine (SAH)

SM: SAH

Structure of complex 8y36

8y36

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8y37

8y37

Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8y38

8y38

Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190.

SM: A1D6G

Structure of complex 8y39

8y39

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8yoo

8yoo

Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline

SM: T1C T1C T1C T1C T1C T1C

Structure of complex 8z8x

8z8x

Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation

SM: G2P

Structure of complex 8z90

8z90

Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2

SM: G2P

Structure of complex 9avr

9avr

Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol

SM: A1AG8

Structure of complex 9b00

9b00

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with berberine analog of chloramphenicol CAM-BER, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.80A resolution

SM: A1AIX A1AIX

Structure of complex 9b4z

9b4z

E. coli 70S ribosome complex (N1-methylated 16S A1408 + arbekacin)

SM: 84G 84G

Structure of complex 9b50

9b50

E. coli 70S ribosome complex (unmethylated 16S A1408 + arbekacin)

SM: 84G 84G

Structure of complex 9b51

9b51

E. coli 70S ribosome complex (N1-methylated 16S A1408 + G418)

SM: GET GET

Structure of complex 9bh5

9bh5

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE

Structure of complex 9blf

9blf

SARS-CoV-2 core polymerase complex inhibited by araCTP

SM: HF4

Structure of complex 9bs0

9bs0

YphC-treated 45SYphC particle. Class 5

SM: GNP

Structure of complex 9c3h

9c3h

Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.

SM: B3P

Structure of complex 9c4g

9c4g

Cutibacterium acnes 50S ribosomal subunit with Clindamycin bound

SM: CLY

Structure of complex 9cai

9cai

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE

Structure of complex 9cn3

9cn3

Human 39S mitoribosome in complex with antibiotic Linezolid

SM: ZLD

Structure of complex 9d0g

9d0g

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with O-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1F A1A1F

Structure of complex 9d0h

9d0h

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with C-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1J A1A1J

Structure of complex 9d0i

9d0i

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Se-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

SM: A1A1K A1A1K

Structure of complex 9d0j

9d0j

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with BT-33, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1L A1A1L

Structure of complex 9dfe

9dfe

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin and protein Y at 2.60A resolution

SM: ARG

Structure of complex 9dov

9dov

Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B

SM: HYG

Structure of complex 9dp7

9dp7

Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B, Class II

SM: HYG

Structure of complex 9dpl

9dpl

Human LysRS bound to cellular modified tRNA-Lys3 and AIMP2

SM: AMP

Structure of complex 9dts

9dts

Crystal structure of the human eIF4A1/AMPPNP/amidino-rocaglate/polypurine RNA complex

SM: A1BB1 A1BB1 A1BB1 A1BB1

Structure of complex 9e6q

9e6q

Cryo-EM structure of the Pyrobaculum calidifontis 50S ribosomal subunit in complex with Dri

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9e71

9e71

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9e7f

9e7f

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome in complex with Dri

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9evs

9evs

Structure of the flowering plant mitoribosome with P-site tRNA

SM: CLM

Structure of complex 9ey1

9ey1

Human mitochondrial RNase Z with tRNA-His precursor

SM: GTP

Structure of complex 9f1b

9f1b

Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E

SM: SPM SPM SPM

Structure of complex 9f1c

9f1c

Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E

SM: SPM SPM SPM

Structure of complex 9f1d

9f1d

Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK

SM: SPM SPM SPM

Structure of complex 9f37

9f37

Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10)

SM: CTP GTP

Structure of complex 9fco

9fco

Structure of E. coli 30S-IF1-IF3-mRNA-Kasugamycin complex

SM: KSG

Structure of complex 9fda

9fda

Structure of E. coli 30S-IF1-IF3-mRNA-Edeine complex

SM: EDE

Structure of complex 9fhl

9fhl

High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fib

9fib

Structure of 30S-IF1-IF3-mRNA-GE81112A complex

SM: A1IC4

Structure of complex 9fqz

9fqz

CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1

SM: 3HE ANM GDP HYG

Structure of complex 9fra

9fra

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frk

9frk

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frl

9frl

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM