Complex 8y36
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.65 |
| System mass | 1334.26 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Staphylococcus |
| RCSB PDB Entry | 8y36 |
| Reference | Ma Cong-Xuan, Li Ye, Liu Wen-Tian, Li Yun, Zhao Fei, Lian Xiao-Tian, Ding Jing, Liu Si-Meng, Liu Xie-Peng, Fan Bing-Zhi, Liu Li-Yong, Xue Feng, Li Jian, Zhang Jue-Ru, Xue Zhao, Pei Xiao-Tong, Lin Jin-Zhong, Liang Jian-Hua. 2024. Synthetic macrolides overcoming MLSBK-resistant pathogens Cell Discovery |
| Equivalence Class |
NR_all_90633.30
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | A1D6G |
| Residue | . / 3001 |
| Chain | EA / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/A: rRNA |
| RNA family global | rRNA |
| Volume | 580.70 Å3 |
| Hydrophobicity | 0.240 |
| Hydrophilicity | 1.210 |
| Buriedness | 0.753 |
| Don/acc character | 1.247 |
| SiteScore | 1.187 |
| D Score | 0.997 |
| Kd | — |