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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 8pnq

8pnq

Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A

SM: 2KH

Structure of complex 8psx

8psx

Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation)

SM: A0I

Structure of complex 8psz

8psz

Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)

SM: A0I

Structure of complex 8pv1

8pv1

Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure

SM: GTP

Structure of complex 8pv2

8pv2

Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1

SM: GTP

Structure of complex 8pv3

8pv3

Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure

SM: GTP

Structure of complex 8pv4

8pv4

Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure

SM: GTP

Structure of complex 8pv5

8pv5

Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite structure

SM: GTP

Structure of complex 8pv7

8pv7

Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure

SM: GTP

Structure of complex 8pvk

8pvk

Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure

SM: GTP

Structure of complex 8pvl

8pvl

Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure

SM: GTP

Structure of complex 8q5i

8q5i

Structure of Candida albicans 80S ribosome in complex with cephaeline

SM: K16 K16 K16 SPK

Structure of complex 8qk7

8qk7

E167K RF2 on E. coli 70S release complex with UAA

SM: SPM SPM

Structure of complex 8qrk

8qrk

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1

SM: NAD SPM SRY

Structure of complex 8qrl

8qrl

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2

SM: NAD

Structure of complex 8qrm

8qrm

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3

SM: NAD SPM SRY

Structure of complex 8qrn

8qrn

mt-SSU in GTPBP8 knock-out cells, state 4

SM: NAD SPM SRY

Structure of complex 8qyx

8qyx

Human 60S ribosomal subunit

SM: ATP SPM SPM SPM SPM SPM

Structure of complex 8qz8

8qz8

Tilapia Lake Virus polymerase in vRNA pre-termination state (transcriptase conformation)

SM: G2P

Structure of complex 8r6y

8r6y

Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]

SM: 2KH

Structure of complex 8rri

8rri

Human mitochondrial ribosome in complex with antibiotic tigecycline

SM: T1C T1C T1C

Structure of complex 8rxh

8rxh

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN

SM: A1H4F

Structure of complex 8s1p

8s1p

YlmH bound to PtRNA-50S

SM: CLM

Structure of complex 8s8w

8s8w

SARS-CoV-2 nsp10-16 methyltransferase in complex with Sangivamycin and m7GpppA-RNA (Cap0-RNA)

SM: SAM SGV

Structure of complex 8s8x

8s8x

SARS-CoV-2 nsp10-16 methyltransferase in complex with Toyocamycin and m7GpppA-RNA (Cap0-RNA)

SM: TO1

Structure of complex 8scb

8scb

Terminating ribosome with SRI-41315

SM: ZVM

Structure of complex 8sq9

8sq9

SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate

SM: WSB

Structure of complex 8sqj

8sqj

SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode

SM: VSN

Structure of complex 8sqk

8sqk

SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate

SM: VSN VSN

Structure of complex 8syl

8syl

Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs

SM: AKN AKN

Structure of complex 8t2x

8t2x

Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, A-site tRNA, messenger RNA and eIF5A, PRE

SM: 3HE

Structure of complex 8t2y

8t2y

Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA, messenger RNA, PRE

SM: 3HE

Structure of complex 8t2z

8t2z

Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA, messenger RNA, POST

SM: 3HE

Structure of complex 8t30

8t30

Hypomethylated yeast 80S bound with cycloheximide, unmodified U2921, mid rotated

SM: 3HE

Structure of complex 8t3a

8t3a

Hypomethylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, sordarin, and hibernating factor Los2

SM: GDP

Structure of complex 8t3c

8t3c

Hypomethylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II

SM: GDP

Structure of complex 8t3e

8t3e

Hypomethylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure IV

SM: GDP

Structure of complex 8t8b

8t8b

Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution

SM: ARG ARG

Structure of complex 8t8c

8t8c

Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution

SM: ARG ARG

Structure of complex 8tg4

8tg4

tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with ADP-ribose-2"-phosphate and 2'-OH RNA

SM: 9SO

Structure of complex 8ub7

8ub7

Diversity-generating retroelement (DGR) ribonucleoprotein reverse transcriptase - Active state (N-occupied)

SM: DCP

Structure of complex 8ud6

8ud6

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution

SM: WC9 WC9

Structure of complex 8ud7

8ud7

Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution

SM: WC9 WC9

Structure of complex 8ud8

8ud8

Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution

SM: WC9

Structure of complex 8uiw

8uiw

yjdF riboswitch from R. gauvreauii in complex with chelerythrine bound to Fab BL3-6 S97N

SM: CTI CTI

Structure of complex 8ut0

8ut0

Eukaryotic 80S ribosome with Reh1, eIF5A and A/P site tRNA

SM: 3HE

Structure of complex 8uta

8uta

yjdF riboswitch from R. gauvreauii in complex with proflavine bound to Fab BL3-6 S97N

SM: PRL PRL

Structure of complex 8uti

8uti

Eukaryotic 80S ribosome with Reh1 and A/P site tRNA

SM: 3HE

Structure of complex 8uvr

8uvr

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with spectinomycin, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.60A resolution

SM: SCM SCM

Structure of complex 8uvs

8uvs

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with spectinomycin derivative 2694, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.75A resolution

SM: Y7K Y7K

Structure of complex 8vft

8vft

Translating 80S rabbit ribosome stalled by emetine with eEF2

SM: 34G

Structure of complex 8vpk

8vpk

Structure of Mycobacterium smegmatis 50S ribosomal subunit bound to HflX and erythromycin:50S-HflX-B-Ery

SM: ERY

Structure of complex 8vr4

8vr4

Structure of Mycobacterium smegmatis 50S ribosomal subunit bound to HflX and erythromycin:50S-HflX-A-Ery

SM: ERY

Structure of complex 8vr8

8vr8

Structure of Mycobacterium smegmatis 50S ribosomal subunit bound to HflX and chloramphenicol:50S-HflX-B-Clm

SM: CLM

Structure of complex 8vrl

8vrl

Structure of Mycobacterium smegmatis 50S ribosomal subunit bound to HflX and chloramphenicol:50S-HflX-A-Clm

SM: CLM

Structure of complex 8vtw

8vtw

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolone MCX-128 and protein Y at 2.35A resolution

SM: ARG ARG

Structure of complex 8vty

8vty

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with ciprofloxacin and protein Y at 2.60A resolution

SM: ARG ARG CPF CPF

Structure of complex 8vuo

8vuo

Crystal structure of SARS-CoV-2 nsp16/nsp10 in complex with Cap-1 RNA

SM: SAH SAH

Structure of complex 8vvp

8vvp

Codon sampling state obtained from Anisomycin-treated mammalian ribosomes

SM: ANM SPM SPM

Structure of complex 8vvq

8vvq

Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from merged datasets

SM: 5GP ANM