Complex 8qrl
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.34 |
| System mass | 1179.39 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 8qrl |
| Reference | Cipullo Miriam, Valentín Gesé Genís, Gopalakrishna Shreekara, Krueger Annika, Lobo Vivian, Pirozhkova Maria A., Marks James, Páleníková Petra, Shiriaev Dmitrii, Liu Yong, Misic Jelena, Cai Yu, Nguyen Minh Duc, Abdelbagi Abubakar, Li Xinping, Minczuk Michal, Hafner Markus, Benhalevy Daniel, Sarshad Aishe A., Atanassov Ilian, Hällberg B. Martin, Rorbach Joanna. 2024. GTPBP8 plays a role in mitoribosome formation in human mitochondria Nature Communications |
| Equivalence Class |
NR_all_93855.32
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | NAD |
| Residue | . / 1701 |
| Chain | FA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/A: rRNA |
| RNA family global | rRNA |
| Volume | 740.54 Å3 |
| Hydrophobicity | 0.384 |
| Hydrophilicity | 1.151 |
| Buriedness | 0.837 |
| Don/acc character | 1.170 |
| SiteScore | 1.243 |
| D Score | 1.067 |
| Kd | — |