Complex 8qz8
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.13 |
| System mass | 182.38 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Tilapinevirus |
| RCSB PDB Entry | 8qz8 |
| Reference | Arragain Benoit, Pelosse Martin, Thompson Albert, Cusack Stephen. 2023. Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family Nature Communications |
| Equivalence Class |
NR_all_41190.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | G2P |
| Residue | . / 601 |
| Chain | G / B |
| Non-redundant | True |
| Interacting RNA chains | E/P, D/V |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | D/V: unknown, E/P: unknown |
| RNA family global | unknown |
| Volume | 548.80 Å3 |
| Hydrophobicity | 0.406 |
| Hydrophilicity | 1.480 |
| Buriedness | 0.820 |
| Don/acc character | 0.652 |
| SiteScore | 1.082 |
| D Score | 0.950 |
| Kd | — |