Complex 8r6y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.40 |
| System mass | 255.92 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bandavirus |
| RCSB PDB Entry | 8r6y |
| Reference | Williams Harry M, Thorkelsson Sigurdur R, Vogel Dominik, Busch Carola, Milewski Morlin, Cusack Stephen, Grünewald Kay, Quemin Emmanuelle R J, Rosenthal Maria. 2024. Structural snapshots of phenuivirus cap-snatching and transcription Nucleic Acids Research |
| Equivalence Class |
NR_all_00699.3,
NR_all_39866.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 2KH |
| Residue | . / 2101 |
| Chain | F / A |
| Non-redundant | False |
| Interacting RNA chains | D/G, C/T |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | C/T: unknown, D/G: unknown |
| RNA family global | unknown |
| Volume | 416.75 Å3 |
| Hydrophobicity | 1.022 |
| Hydrophilicity | 1.138 |
| Buriedness | 0.877 |
| Don/acc character | 0.970 |
| SiteScore | 1.120 |
| D Score | 1.095 |
| Kd | — |