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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 8uti

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 RNA

 Protein

 DNA

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System information

Experimental technique Electron Microscopy
Experimental resolution 3.13
System mass 3139.29 kDa
Deposition year 2023
Molecule type RNA/Protein
# RNA entities 1
Organism Saccharomyces
RCSB PDB Entry 8uti
Reference Musalgaonkar Sharmishtha, Yelland James N., Chitale Ruta, Rao Shilpa, Ozadam Hakan, Taylor David W., Cenik Can, Johnson Arlen W.. 2025. The assembly factor Reh1 is released from the ribosome during its initial round of translation Nature Communications
Equivalence Class NR_all_90506.85
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound 3HE
Residue . / 3401
Chain EC / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains A/A: rRNA
RNA family global rRNA
Volume 297.72 Å3
Hydrophobicity 0.352
Hydrophilicity 0.851
Buriedness 0.625
Don/acc character 1.733
SiteScore 1.027
D Score 0.895
Kd