Harnessing RIBOnucleic acid - Small molecules Structures
Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)
SM: 2KH
Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)
Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.
SM: 3HE
In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state
SM: ATP UTP
Crystal structure of human zinc finger antiviral protein bound to RNA
SM: SPM
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA
SM: FME
CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP
SM: GDP
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
SM: ZC0
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
SM: RD8
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
SM: U7V
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
SM: U7Y
E. coli 50S ribosome bound to compounds 47 and VS1
SM: O7S
Structure of a drug-like compound stalled human translation termination complex
SM: MVM
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution
SM: ARG ERY
Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution
SM: TEL
Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog
SM: V6D
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution
SM: V7A
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
SM: DI0
E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).
E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).
Structure of human ribosome in classical-PRE state
Structure of human ribosome in POST state
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
SM: OCW
Tetracenomycin X bound to the human ribosome
55S mammalian mitochondrial ribosome with mtEFG1 and P site fMet-tRNAMet (POST)
SM: 5GP GNP SPM
55S mammalian mitochondrial ribosome with mtEFG1 and two tRNAMet (TI-POST)
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
SM: GTP
Rix1-Rea1 pre-60S particle - full composite structure
Acinetobacter baumannii ribosome-amikacin complex - 30S subunit body
SM: AKN
Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit
SM: T1C
Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head
The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state
SM: NAD SPM
The structure of the large subunit of the mitoribosome from Neurospora crassa
The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa
The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site
The structure of the mitoribosome from Neurospora crassa with bound tRNA at the P-site
Human mitochondrial ribosome in complex with ribosome recycling factor
SM: DOL
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Human mitochondrial ribosome in complex with mRNA and P-site tRNA
Human mitochondrial ribosome in complex with E-site tRNA
Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA
Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA
Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA
Cryo-EM structure of a late human pre-40S ribosomal subunit - State G
SM: ATP
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
SM: QTZ
SM: QU2
50S Deinococcus radiodurans ribosome bounded with mycinamicin IV
SM: MIV
Structure of the human mitoribosome in the post translocation state bound to mtEF-G1
SM: GCP
Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP
SM: GE6
Human pre-Bact-1 spliceosome core structure
SM: IHP
Human pre-Bact-2 spliceosome
mt-SSU from Trypanosoma cruzi in complex with mt-IF-3.
SM: UTP
Context-specific inhibition of eukaryotic translation by macrolide antibiotics
E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain.
SM: ERY SY5
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)
Cryo-EM structure of Favipiravir bound to replicating polymerase complex of SARS-CoV-2 in the pre-catalytic state.
Current selection range: to