Harnessing RIBOnucleic acid - Small molecules Structures
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High-resolution cryo-EM structure of the human 80S ribosome
SM: HMT HYG
Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3
SM: NAD SPM SRY
Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF2 and IF3
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.
SM: ERY
Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)
SM: 2KH
Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)
Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.
SM: 3HE
In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state
SM: ATP UTP
Crystal structure of human zinc finger antiviral protein bound to RNA
SM: SPM
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA
SM: FME
CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP
SM: GDP
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
SM: ZC0
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
SM: RD8
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
SM: U7V
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
SM: U7Y
E. coli 50S ribosome bound to compounds 47 and VS1
SM: O7S
Structure of a drug-like compound stalled human translation termination complex
SM: MVM
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution
SM: ARG ARG ERY ERY
Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution
SM: TEL TEL
Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog
SM: V6D
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution
SM: V7A V7A
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
SM: DI0
E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).
E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).
Structure of human ribosome in classical-PRE state
Structure of human ribosome in POST state
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
SM: OCW
Tetracenomycin X bound to the human ribosome
55S mammalian mitochondrial ribosome with mtEFG1 and P site fMet-tRNAMet (POST)
SM: 5GP 5GP GNP SPM SPM SPM
55S mammalian mitochondrial ribosome with mtEFG1 and two tRNAMet (TI-POST)
SM: 5GP GNP SPM SPM SPM
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
SM: GTP
Rix1-Rea1 pre-60S particle - full composite structure
Acinetobacter baumannii ribosome-amikacin complex - 30S subunit body
SM: AKN
Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit
SM: T1C T1C T1C
Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head
SM: T1C
The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state
SM: NAD SPM
The structure of the large subunit of the mitoribosome from Neurospora crassa
The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa
The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site
The structure of the mitoribosome from Neurospora crassa with bound tRNA at the P-site
Human mitochondrial ribosome in complex with ribosome recycling factor
SM: DOL
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Human mitochondrial ribosome in complex with mRNA and P-site tRNA
Human mitochondrial ribosome in complex with E-site tRNA
Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA
Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA
Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA
Cryo-EM structure of a late human pre-40S ribosomal subunit - State G
SM: ATP
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
SM: QTZ
SM: QU2
50S Deinococcus radiodurans ribosome bounded with mycinamicin IV
SM: MIV
Structure of the human mitoribosome in the post translocation state bound to mtEF-G1
SM: GCP
Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP
SM: GE6
Human pre-Bact-1 spliceosome core structure
SM: IHP
Human pre-Bact-2 spliceosome
mt-SSU from Trypanosoma cruzi in complex with mt-IF-3.
SM: UTP
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Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
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Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
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Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8