Complex 6y2l
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.00 |
| System mass | 3785.61 kDa |
| Deposition year | 2020 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 6y2l |
| Reference | Bhaskar Varun, Graff-Meyer Alexandra, Schenk Andreas D., Cavadini Simone, von Loeffelholz Ottilie, Natchiar S. Kundhavai, Artus-Revel Caroline G., Hotz Hans-Rudolf, Bretones Gabriel, Klaholz Bruno P., Chao Jeffrey A.. 2020. Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes Cell Reports |
| Equivalence Class |
NR_all_65061.63
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3HE |
| Residue | . / 5101 |
| Chain | DC / L5 |
| Non-redundant | True |
| Interacting RNA chains | D/L5 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | D/L5: rRNA |
| RNA family global | rRNA |
| Volume | 281.95 Å3 |
| Hydrophobicity | 0.169 |
| Hydrophilicity | 1.053 |
| Buriedness | 0.638 |
| Don/acc character | 1.213 |
| SiteScore | 0.945 |
| D Score | 0.768 |
| Kd | — |