Complex 6t0v
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.02 |
| System mass | 285.41 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Alphainfluenzavirus |
| RCSB PDB Entry | 6t0v |
| Reference | Wandzik Joanna M., Kouba Tomas, Karuppasamy Manikandan, Pflug Alexander, Drncova Petra, Provaznik Jan, Azevedo Nayara, Cusack Stephen. 2020. A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase Cell |
| Equivalence Class |
NR_all_98744.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 2KH |
| Residue | . / 801 |
| Chain | J / B |
| Non-redundant | True |
| Interacting RNA chains | E/R, F/M |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/R: unknown, F/M: mRNA |
| RNA family global | mRNA |
| Volume | 705.21 Å3 |
| Hydrophobicity | 0.061 |
| Hydrophilicity | 1.609 |
| Buriedness | 0.842 |
| Don/acc character | 0.672 |
| SiteScore | 1.096 |
| D Score | 0.921 |
| Kd | — |