Complex 6tnu
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.10 |
| System mass | 3038.61 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Saccharomyces |
| RCSB PDB Entry | 6tnu |
| Reference | Buschauer Robert, Matsuo Yoshitaka, Sugiyama Takato, Chen Ying-Hsin, Alhusaini Najwa, Sweet Thomas, Ikeuchi Ken, Cheng Jingdong, Matsuki Yasuko, Nobuta Risa, Gilmozzi Andrea, Berninghausen Otto, Tesina Petr, Becker Thomas, Coller Jeff, Inada Toshifumi, Beckmann Roland. 2020. The Ccr4-Not complex monitors the translating ribosome for codon optimality Science |
| Equivalence Class |
NR_all_90506.85
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3HE |
| Residue | . / 3402 |
| Chain | IC / BQ |
| Non-redundant | True |
| Interacting RNA chains | LA/BQ |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | LA/BQ: rRNA |
| RNA family global | rRNA |
| Volume | 261.02 Å3 |
| Hydrophobicity | 0.216 |
| Hydrophilicity | 0.903 |
| Buriedness | 0.649 |
| Don/acc character | 1.177 |
| SiteScore | 0.908 |
| D Score | 0.925 |
| Kd | — |