Complex 6qzp
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.90 |
| System mass | 3254.79 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 6qzp |
| Reference | Natchiar S. Kundhavai, Myasnikov Alexander G., Kratzat Hanna, Hazemann Isabelle, Klaholz Bruno P.. 2017. Visualization of chemical modifications in the human 80S ribosome structure Nature |
| Equivalence Class |
NR_all_46995.72,
NR_all_65061.63
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | HMT |
| Residue | . / 5374 |
| Chain | QM / L5 |
| Non-redundant | True |
| Interacting RNA chains | A/L5 |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/L5: rRNA |
| RNA family global | rRNA |
| Volume | 761.80 Å3 |
| Hydrophobicity | 0.262 |
| Hydrophilicity | 1.339 |
| Buriedness | 0.795 |
| Don/acc character | 1.141 |
| SiteScore | 1.215 |
| D Score | 0.981 |
| Kd | — |
| Compound | HYG |
| Residue | . / 2039 |
| Chain | CT / S2 |
| Non-redundant | True |
| Interacting RNA chains | UA/S2 |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | UA/S2: rRNA |
| RNA family global | rRNA |
| Volume | 120.05 Å3 |
| Hydrophobicity | 0.072 |
| Hydrophilicity | 1.296 |
| Buriedness | 0.653 |
| Don/acc character | 1.589 |
| SiteScore | 0.596 |
| D Score | 0.430 |
| Kd | — |