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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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2077 RNA-SM complexes found
Structure of complex 6hko

6hko

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP

SM: G2P

Structure of complex 6hlq

6hlq

Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP

SM: G2P

Structure of complex 6hlr

6hlr

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)

SM: G2P

Structure of complex 6hmo

6hmo

Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier

SM: GDZ

Structure of complex 6i0y

6i0y

TnaC-stalled ribosome complex with the titin I27 domain folding close to the ribosomal exit tunnel

SM: TRP

Structure of complex 6i1l

6i1l

Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target

SM: CIT CIT CIT CIT CIT CIT

Structure of complex 6i7v

6i7v

Ribosomal protein paralogs bL31 and bL36

SM: 1PE 1PE PG4 PG4 PG4

Structure of complex 6i9r

6i9r

Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin

SM: H8T

Structure of complex 6izp

6izp

Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad

SM: B2R B2R

Structure of complex 6jbf

6jbf

Crystal structure of the bacterial ribosomal decoding site in complex with 4'-deoxy-4'-fluoro neamine analog (axial 4'-F)

SM: V71

Structure of complex 6jbg

6jbg

Crystal structure of the bacterial ribosomal decoding site in complex with 4'-deoxy-4'-fluoro neamine analog (equatorial 4'-F)

SM: S81

Structure of complex 6jjh

6jjh

Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4

SM: POH POH

Structure of complex 6jji

6jji

Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 (1:1)

SM: POH

Structure of complex 6k32

6k32

RdRp complex

SM: UTP

Structure of complex 6kwr

6kwr

Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form)

SM: DCT

Structure of complex 6las

6las

the wildtype SAM-VI riboswitch bound to SAM

SM: SAM SAM

Structure of complex 6lau

6lau

the wildtype SAM-VI riboswitch bound to SAH

SM: GTP SAH SAH

Structure of complex 6lax

6lax

the mutant SAM-VI riboswitch (U6C) bound to SAM

SM: SAM SAM

Structure of complex 6laz

6laz

the wildtype SAM-VI riboswitch bound to a N-mustard SAM analog M1

SM: E7X E7X

Structure of complex 6mkn

6mkn

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin

SM: PAR

Structure of complex 6mpf

6mpf

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin

SM: PAR

Structure of complex 6mpi

6mpi

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin

SM: PAR

Structure of complex 6n5k

6n5k

Structure of Human pir-miRNA-449c Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n5n

6n5n

Structure of Human pir-miRNA-208a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n5o

6n5o

Structure of Human pir-miRNA-202 Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n5p

6n5p

Structure of Human pir-miRNA-340 Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n5q

6n5q

Structure of Human pir-miRNA-378a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n5s

6n5s

Structure of Human pir-miRNA-320b-2 Apical Loop and One-base-pair Stem Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA 5GP

Structure of complex 6n5t

6n5t

Structure of Human pir-miRNA-378a Apical Loop Fused to the YdaO Riboswitch Scaffold

SM: 2BA 2BA

Structure of complex 6n9u

6n9u

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

SM: TTP

Structure of complex 6n9v

6n9v

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

SM: TTP

Structure of complex 6n9w

6n9w

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)

SM: TTP

Structure of complex 6n9x

6n9x

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

SM: TTP

Structure of complex 6nbj

6nbj

Qri7

SM: ATP

Structure of complex 6nd5

6nd5

Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution

SM: CLM CLM

Structure of complex 6nd6

6nd6

Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution

SM: ERY ERY

Structure of complex 6o97

6o97

Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution

SM: LUJ LUJ LUJ LUJ LUJ LUJ

Structure of complex 6od9

6od9

Co-crystal structure of the Fusobacterium ulcerans ZTP riboswitch using an X-ray free-electron laser

SM: AMZ AMZ

Structure of complex 6of1

6of1

Crystal structure of the Thermus thermophilus 70S ribosome in complex with dirithromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.80A resolution

SM: DI0 DI0

Structure of complex 6of6

6of6

Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site

SM: AMP PAR PAR

Structure of complex 6ofx

6ofx

Non-rotated ribosome (Structure I)

SM: FME

Structure of complex 6ogz

6ogz

In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state

SM: UTP

Structure of complex 6oj2

6oj2

Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site

SM: PAR PAR

Structure of complex 6okk

6okk

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

SM: 34G

Structure of complex 6ole

6ole

Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs

SM: MVM

Structure of complex 6olf

6olf

Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs

SM: MVM

Structure of complex 6olg

6olg

Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)

SM: MVM

Structure of complex 6oli

6oli

Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)

SM: MVM

Structure of complex 6olz

6olz

Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA

SM: MVM

Structure of complex 6om0

6om0

Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs

SM: MVM

Structure of complex 6om6

6om6

Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA

SM: KKL

Structure of complex 6om7

6om7

Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs

SM: MVM

Structure of complex 6ope

6ope

Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site

SM: PAR PAR

Structure of complex 6ord

6ord

Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site

SM: PAR PAR

Structure of complex 6oy5

6oy5

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min

SM: GTP

Structure of complex 6oy6

6oy6

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min

SM: GTP

Structure of complex 6p1s

6p1s

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated AMP

SM: ATP

Structure of complex 6p1u

6p1u

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated CMP

SM: CTP

Structure of complex 6p2h

6p2h

Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches

SM: GNG

Structure of complex 6p71

6p71

X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter

SM: UTP