Complex 6ofx
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.30 |
| System mass | 2162.83 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 6ofx |
| Reference | Svidritskiy Egor, Demo Gabriel, Loveland Anna B, Xu Chen, Korostelev Andrei A. 2019. Extensive ribosome and RF2 rearrangements during translation termination eLife |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | FME |
| Residue | . / 101 |
| Chain | CB / 5 |
| Non-redundant | True |
| Interacting RNA chains | YA/1 |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | YA/1: rRNA |
| RNA family global | rRNA |
| Volume | 509.01 Å3 |
| Hydrophobicity | 0.254 |
| Hydrophilicity | 1.047 |
| Buriedness | 0.694 |
| Don/acc character | 2.250 |
| SiteScore | 1.147 |
| D Score | 1.015 |
| Kd | — |