Harnessing RIBOnucleic acid - Small molecules Structures
Crystal structure of CAG repeats with synthetic CMBL3b compound
SM: J48
Crystal structure of seleno-derivative CAG repeats with synthetic CMBL4 compound
SM: J4H
Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid
SM: AMP JJH
High-resolution cryo-EM structure of the human 80S ribosome
SM: HMT HYG
Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate
SM: CTP
Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3
SM: NAD SPM SRY
Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF2 and IF3
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.
SM: ERY
Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)
SM: 2KH
Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of K+, Mg2+ and 5'-exon
SM: EPE SPM
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of Na+, Mg2+ and 5'-exon
SM: EPE
Structure of Oceanobacillus iheyensis group II intron U-mutant (C289U/C358U/G385A) in the presence of K+, Mg2+ and 5'-exon
Structure of Oceanobacillus iheyensis group II intron U-mutant (C289U/C358U/G385A) in the presence of Na+, Mg2+ and 5'-exon
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine monophosphate (AMP)
SM: AMP
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Nicotinamide adenine dinucleotide, reduced (NADH)
SM: NAI
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine diphosphate (ADP)
SM: ADP
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine 5-triphosphate (ATP)
SM: ATP
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Cordycepin 5-triphosphate (3-dATP)
SM: 3AT
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with N6-Methyl-adenosine-5'-triphosphate (m6ATP)
SM: N6E
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Nicotinamide adenine dinucleotide (NAD+)
SM: NAD
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine 3-phosphate 5-phosphosulfate (APPS)
SM: PPS
Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Nicotinamide adenine dinucleotide, reduced (NADH); soaking with Manganese(II) (Mn2+)
Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.
SM: 3HE
In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state
SM: ATP UTP
RNA-monomer complex containing pyrophosphate linkage
SM: EQ4
RNA hairpin structure containing one TNA nucleotide as template
SM: C5P
RNA hairpin structure containing one TNA nucleotide as primer
RNA duplex, bound with TNA monomer
SM: TG
RNA hairpin, bound with TNA monomer
RNA duplex bound with TNA 3'-3' imidazolium dimer
SM: Q1V
Structure of guanine riboswitch bound to N2-acetyl guanine
SM: Q44
Guanine riboswitch bound to 8-aminoguanine
SM: ANG
Guanine riboswitch bound to O6-cyclohexylmethyl guanine
SM: CMG
Crystal structure of human zinc finger antiviral protein bound to RNA
SM: SPM
SAM-bound SAM-IV riboswitch
SM: SAM
Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin
SM: YO3
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E
SM: APC
Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp
SM: G2P
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)
SM: GTP
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)
E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)
SM: D4M
E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)
SM: UTP
E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)
SM: 2DA
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA
SM: FME
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
SM: QSA
SM: QW4
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5
SM: QSV
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MQC
SM: MQC
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP
SM: QSY
Metabolite-bound PreQ1 riboswitch with Mn2+
SM: PRF
CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP
SM: GDP
Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP
SM: DCP
Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP
SM: CH1
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
SM: ZC0
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
SM: RD8
Current selection range: to