Complex 6lax
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.70 |
| System mass | 69.22 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bifidobacterium |
| RCSB PDB Entry | 6lax |
| Reference | Sun Aiai, Gasser Catherina, Li Fudong, Chen Hao, Mair Stefan, Krasheninina Olga, Micura Ronald, Ren Aiming. 2019. SAM-VI riboswitch structure and signature for ligand discrimination Nature Communications |
| Equivalence Class |
NR_all_47836.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAM |
| Residue | . / 101 |
| Chain | F / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 83.35 Å3 |
| Hydrophobicity | 0.980 |
| Hydrophilicity | 0.878 |
| Buriedness | 0.705 |
| Don/acc character | 1.256 |
| SiteScore | 0.867 |
| D Score | 0.677 |
| Kd | — |
| Compound | SAM |
| Residue | . / 101 |
| Chain | G / B |
| Non-redundant | True |
| Interacting RNA chains | E/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | E/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 100.84 Å3 |
| Hydrophobicity | 1.268 |
| Hydrophilicity | 1.017 |
| Buriedness | 0.735 |
| Don/acc character | 1.260 |
| SiteScore | 0.771 |
| D Score | 0.719 |
| Kd | — |