Complex 6lau
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.11 |
| System mass | 69.85 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bifidobacterium |
| RCSB PDB Entry | 6lau |
| Reference | Sun Aiai, Gasser Catherina, Li Fudong, Chen Hao, Mair Stefan, Krasheninina Olga, Micura Ronald, Ren Aiming. 2019. SAM-VI riboswitch structure and signature for ligand discrimination Nature Communications |
| Equivalence Class |
NR_all_47836.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 103 |
| Chain | H / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 132.40 Å3 |
| Hydrophobicity | 0.126 |
| Hydrophilicity | 0.666 |
| Buriedness | 0.543 |
| Don/acc character | 2.307 |
| SiteScore | 0.866 |
| D Score | 0.725 |
| Kd | — |
| Compound | SAH |
| Residue | . / 101 |
| Chain | F / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 105.64 Å3 |
| Hydrophobicity | 0.431 |
| Hydrophilicity | 0.884 |
| Buriedness | 0.639 |
| Don/acc character | 2.703 |
| SiteScore | 0.816 |
| D Score | 0.618 |
| Kd | — |
| Compound | SAH |
| Residue | . / 101 |
| Chain | I / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 100.16 Å3 |
| Hydrophobicity | 0.734 |
| Hydrophilicity | 0.665 |
| Buriedness | 0.629 |
| Don/acc character | 2.628 |
| SiteScore | 0.913 |
| D Score | 0.763 |
| Kd | — |