HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 6i0y

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.20
System mass 1414.24 kDa
Deposition year 2018
Molecule type RNA/Protein
# RNA entities 1
Organism Escherichia
RCSB PDB Entry 6i0y
Reference Tian Pengfei, Steward Annette, Kudva Renuka, Su Ting, Shilling Patrick J., Nickson Adrian A., Hollins Jeffrey J., Beckmann Roland, von Heijne Gunnar, Clarke Jane, Best Robert B.. 2018. Folding pathway of an Ig domain is conserved on and off the ribosome Proceedings of the National Academy of Sciences
Equivalence Class NR_all_83717.187
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound TRP
Residue . / 3001
Chain MA / A
Non-redundant True
Interacting RNA chains K/A
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains K/A: rRNA
RNA family global rRNA
Volume 537.82 Å3
Hydrophobicity 0.166
Hydrophilicity 1.436
Buriedness 0.798
Don/acc character 0.559
SiteScore 1.217
D Score 0.951
Kd