Complex 6i9r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.90 |
| System mass | 1745.23 kDa |
| Deposition year | 2018 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 6i9r |
| Reference | Sighel Denise, Notarangelo Michela, Aibara Shintaro, Re Angela, Ricci Gianluca, Guida Marianna, Soldano Alessia, Adami Valentina, Ambrosini Chiara, Broso Francesca, Rosatti Emanuele Filiberto, Longhi Sara, Buccarelli Mariachiara, D’Alessandris Quintino G., Giannetti Stefano, Pacioni Simone, Ricci-Vitiani Lucia, Rorbach Joanna, Pallini Roberto, Roulland Sandrine, Amunts Alexey, Mancini Ines, Modelska Angelika, Quattrone Alessandro. 2021. Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth Cell Reports |
| Equivalence Class |
NR_all_12763.37
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | H8T |
| Residue | . / 5129 |
| Chain | CG / A |
| Non-redundant | True |
| Interacting RNA chains | K/A |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | K/A: rRNA |
| RNA family global | rRNA |
| Volume | 671.94 Å3 |
| Hydrophobicity | 0.360 |
| Hydrophilicity | 1.298 |
| Buriedness | 0.865 |
| Don/acc character | 1.567 |
| SiteScore | 0.932 |
| D Score | 1.036 |
| Kd | — |