Complex 6las
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.71 |
| System mass | 69.22 kDa |
| Deposition year | 2019 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bifidobacterium |
| RCSB PDB Entry | 6las |
| Reference | Sun Aiai, Gasser Catherina, Li Fudong, Chen Hao, Mair Stefan, Krasheninina Olga, Micura Ronald, Ren Aiming. 2019. SAM-VI riboswitch structure and signature for ligand discrimination Nature Communications |
| Equivalence Class |
NR_all_47836.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAM |
| Residue | . / 101 |
| Chain | F / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 119.36 Å3 |
| Hydrophobicity | 0.336 |
| Hydrophilicity | 0.860 |
| Buriedness | 0.641 |
| Don/acc character | 2.409 |
| SiteScore | 0.889 |
| D Score | 0.713 |
| Kd | — |
| Compound | SAM |
| Residue | . / 101 |
| Chain | G / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 90.90 Å3 |
| Hydrophobicity | 1.040 |
| Hydrophilicity | 0.676 |
| Buriedness | 0.696 |
| Don/acc character | 1.944 |
| SiteScore | 0.894 |
| D Score | 0.720 |
| Kd | — |