Harnessing RIBOnucleic acid - Small molecules Structures
Mycoplasma pneumoniae di-ribosome in chloramphenicol-treated cells (following 70S)
SM: CLM
80S yeast ribosome in complex with Methyllissoclimide
SM: XBI
Escherichia coli paused disome complex (queueing 70S non-rotated closed PRE state)
SM: ATP
Mouse RPL39L integrated into the yeast 60S ribosomal subunit
SM: SPM
80S yeast ribosome in complex with Bromolissoclimide
SM: ZWB
Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A
SM: 2KH
Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation)
SM: A0I
Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)
Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure
SM: GTP
Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1
Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure
Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure
Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite structure
Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure
Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure
Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure
Structure of Candida albicans 80S ribosome in complex with cephaeline
SM: K16 SPK
E167K RF2 on E. coli 70S release complex with UAA
Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77
SM: W53
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1
SM: NAD SPM SRY
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2
SM: NAD
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3
mt-SSU in GTPBP8 knock-out cells, state 4
Human 60S ribosomal subunit
SM: ATP SPM
Tilapia Lake Virus polymerase in vRNA pre-termination state (transcriptase conformation)
SM: G2P
Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition
SM: Y59
Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition
SM: Y53
Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]
Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition
SM: YB3
Human mitochondrial ribosome in complex with antibiotic tigecycline
SM: T1C
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and 5'-exon
SM: EPE
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and intronistat B after 1h soaking
SM: VTE
Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and ARN25850 after 1h soaking
SM: VTR
Structure of Oceanobacillus iheyensis group II intron in the presence of Na+, Mg2+, and ARN25850
Structure of Oceanobacillus iheyensis group II intron in the presence of Li+ and Mg2+
Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and intronistat B
Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and ARN25850
SM: EPE VTR
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
SM: A1H4F
YlmH bound to PtRNA-50S
SARS-CoV-2 nsp10-16 methyltransferase in complex with Sangivamycin and m7GpppA-RNA (Cap0-RNA)
SM: SAM SGV
SARS-CoV-2 nsp10-16 methyltransferase in complex with Toyocamycin and m7GpppA-RNA (Cap0-RNA)
SM: TO1
Terminating ribosome with SRI-41315
SM: ZVM
SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate
SM: WSB
SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode
SM: VSN
SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate
RNA duplex bound with GpppA dinucleotide ligand
SM: G3A
GpppA dinucleotide ligand binding to RNA UC template
GpppA dinucleotide binding to RNA CU template
RNA duplex bound with GMP and AMP monomers
SM: 5GP AMP
RNA UU template binding to AMP monomer
SM: AMP
Structure of LINE-1 ORF2p with template:primer hybrid
SM: TTP
RNA duplex bound with imidazolium bridged GA dinucleotide
SM: WZW
Crystal structure of RNA device 43 truncation mutant 3 (U100C), holo state
SM: TAC
Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs
SM: AKN
Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, A-site tRNA, messenger RNA and eIF5A, PRE
SM: 3HE
Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA, messenger RNA, PRE
Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA, messenger RNA, POST
Hypomethylated yeast 80S bound with cycloheximide, unmodified U2921, mid rotated
Hypomethylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, sordarin, and hibernating factor Los2
SM: GDP
Hypomethylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
Current selection range: to