Complex 8p8u
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.23 |
| System mass | 1932.04 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Saccharomyces |
| RCSB PDB Entry | 8p8u |
| Reference | Banerjee Arka, Ataman Meric, Smialek Maciej Jerzy, Mookherjee Debdatto, Rabl Julius, Mironov Aleksei, Mues Lea, Enkler Ludovic, Coto-Llerena Mairene, Schmidt Alexander, Boehringer Daniel, Piscuoglio Salvatore, Spang Anne, Mittal Nitish, Zavolan Mihaela. 2024. Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains Nucleic Acids Research |
| Equivalence Class |
NR_all_90506.85
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SPM |
| Residue | . / 3468 |
| Chain | GD / A |
| Non-redundant | True |
| Interacting RNA chains | E/A |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/A: rRNA |
| RNA family global | rRNA |
| Volume | 669.54 Å3 |
| Hydrophobicity | 0.347 |
| Hydrophilicity | 1.297 |
| Buriedness | 0.866 |
| Don/acc character | 2.286 |
| SiteScore | 1.112 |
| D Score | 1.036 |
| Kd | — |